Sökning: "Glatiramer acetate"

Hittade 4 avhandlingar innehållade orden Glatiramer acetate.

  1. 1. Immunological effects of interferon-beta and glatiramer acetate in multiple sclerosis

    Författare :Yassir Hussien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; Interferon-beta; Glatiramer acetate; Dendritic cells; Mononucealar cells;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which results in demyelination, axonal loss and neurological deficits. The aetiology is unknown, however, immunopathological events, which are believed to be of an autoimmune nature, are considered to be responsible for the development of the disease. LÄS MER

  3. 2. Dimethyl fumarate for treatment of multiple sclerosis : clinical effects and mechanisms

    Författare :Mathias Granqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS). Dimethyl fumarate (DMF) is one of the more recent additions to a rapidly expanding treatment repertoire for MS. LÄS MER

  4. 3. Anti-CD20 therapy in multiple sclerosis : clinical and paraclinical outcomes

    Författare :Alexander Juto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis is a chronic inflammatory disease of the central nervous system and the most common non-traumatic cause of neurological disability in young adults. Rituximab is a B-cell depleting drug targeting the CD20 epitope on B-cells, which drive inflammation in relapsing-remitting multiple sclerosis by acting as antigen-presenting cells to activate T-cell responses against central nervous system autoantigens. LÄS MER

  5. 4. CD4+CD25+ T regulatory cells in multiple sclerosis

    Författare :Prabhakar Putheti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). LÄS MER