Sökning: "Interferon-beta"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet Interferon-beta.

  1. 1. Immunological effects of interferon-beta and glatiramer acetate in multiple sclerosis

    Författare :Yassir Hussien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; Interferon-beta; Glatiramer acetate; Dendritic cells; Mononucealar cells;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which results in demyelination, axonal loss and neurological deficits. The aetiology is unknown, however, immunopathological events, which are believed to be of an autoimmune nature, are considered to be responsible for the development of the disease. LÄS MER

  3. 2. Interferon-beta treatment in multiple sclerosis : analysis of neutralizing antibodies

    Författare :Ajith Sominanda; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a disabling chronic neurological disease with a significant impact on patients lives. There is no cure for MS, but recombinant interferon beta (IFN-beta) is currently the most established disease modifying therapy. LÄS MER

  4. 3. Mechanisms of TRAIL- and Smac mimetic-induced cell death and phenotypical changes in breast cancer

    Författare :Victoria Granqvist; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; TRAIL; Smac mimetics; Cell death; interferon beta; NF-kappa B;

    Sammanfattning : .... LÄS MER

  5. 4. Targeting viral induced TSLP - an airway treatment opportunity

    Författare :Angelica Brandelius; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Respiratory viral infections cause exacerbations of asthma and COPD that cannot be effectively treated today. Thymic Stromal Lymphopoietin (TSLP) is an upstream epithelial cytokine linking the innate and adaptive immune system. Viral stimuli induce epithelial overexpression of TSLP in asthma and COPD. LÄS MER

  7. 5. Consequences of multiple sclerosis for patients in Sweden

    Författare :Sarah Burkill; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This study aimed to consider consequences of multiple sclerosis for patients in Sweden throughout various stages of the life course. The thesis was separated into four constituent papers, which dealt with different aspects of the disease, its symptoms, and implications at different life stages. LÄS MER