Sökning: "GTPase"

Visar resultat 21 - 25 av 94 avhandlingar innehållade ordet GTPase.

  1. 21. Exoenzyme S of Pseudomonas aeruginosa : cellular targets and interaction with 14-3-3

    Författare :Lubna Yasmin; Bengt Hallberg; Joan Olson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ExoS; ADP-ribosylation; 14-3-3 protein; Pseudomonas aeruginosa; Small GTPases; RAS; RAP; Pathology; Patologi;

    Sammanfattning : Pseudomonas aeruginosa is an opportunistic pathogen that is a serious problem for immuno-compromised patients. Toxins such as exoenzyme (Exo) S, ExoT, ExoY and ExoU are secreted and translocated from the bacteria into the eukaryotic cell via the bacterial encoded type III secretion system. LÄS MER

  3. 22. Disassembly and reassembly of the nuclear pore complex

    Författare :Evgeny A. Onischenko; Einar Hallberg; Paul R. Clarke; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The nuclear pore complexes (NPCs) are multiprotein communicative channels spanning the nuclear envelope. In higher eukaryotes NPCs reversibly disassemble during mitosis into distinct nucleoporin subcomplexes. Some cell types (e.g. LÄS MER

  4. 23. The role of RhoD in actin dynamics, receptor trafficking and cancer cell migration

    Författare :Vishal Nehru; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Ras subfamily of Rho GTPases plays an important role in myriads of cell processes, such as actin cytoskeleton dynamics, membrane trafficking and cell migration. Additionally, they also participate in diverse signal transduction pathways that regulate gene transcription, cell survival and cell growth. LÄS MER

  5. 24. Metabolic regulation of nitrogenase in Rhodospirillum rubrum : studies on DRAG and DRAT, the regulatory proteins of dinitrogenase reductase

    Författare :Agneta Norén; Gary Robert; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; biokemi;

    Sammanfattning : Nitrogen fixation is catalyzed by nitrogenase, in an ATP-dependent reaction where dinitrogen is reduced to ammonium. Nitrogenase is a protein complex consisting of two proteins; dinitrogenase and dinitrogenase reductase and the reaction is only carried out by prokaryotes. LÄS MER

  7. 25. Controlling angiogenesis : functional studies of angiomotin

    Författare :Mira Ernkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The expansion of a blood circulatory network by the process of angiogenesis is essential for embryonic as well as postnatal growth. Deregulated blood vessel formation may also negatively contribute to the pathogenesis of diseases, e.g. cancer and diabetic retinopathy. LÄS MER