Sökning: "GTPase"

Visar resultat 16 - 20 av 94 avhandlingar innehållade ordet GTPase.

  1. 16. Cellular targets of Pseudomonas aeruginosa toxin Exoenzyme S

    Författare :Maria Henriksson; Bengt Hallberg; Lars Rönnstrand; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Pseudomonas aeruginosa; ADP-ribosylation; GAP; Ras superfamily; NAD; ExoS; 14-3-3; Cellbiologi; Cell biology; Cellbiologi; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : Pseudomonas aeruginosa is an opportunistic pathogen that can cause life-threatening infections in immunocompromised patients. It uses a type III secretion dependent mechanism to translocate toxic effector proteins directly into the eukaryotic cell. LÄS MER

  3. 17. Nucleotide-Dependent Processes in the Thylakoid Lumen of Plant Chloroplasts

    Författare :Björn Lundin; Cornelia Spetea Wiklund; Zach Adam; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; plant; chloroplast; thylakoid; nucleotide; PSII; PsbO; Biology; Biologi;

    Sammanfattning : Plants, algae and photosynthetic bacteria are able to harvest the sunlight and use its energy to transform water and carbon dioxide to carbohydrate molecules and oxygen, both important to sustain life on Earth. This process is called photosynthesis and is the route by which almost all energy enters the biosphere. LÄS MER

  4. 18. Rho-GTPases in Rheumatoid Arthritis

    Författare :Eric Malmhäll-Bah; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rho-GTPases; rheumatoid arthritis; innate immunity; adaptive immunity; RA treatment;

    Sammanfattning : The success of alleviating rheumatoid arthritis (RA) symptoms is complicated by both heterogeneity of the disease and lack of predictive markers to guide treatment options. Deregulated Rho-GTPases, a family of hydrolase enzymes catalyzing guanosine triphospate (GTP) to guanosine diphospate (GDP), have a detrimental role in many diseases including RA. LÄS MER

  5. 19. The role of multifunctional scaffolding proteins in the synaptic vesicle cycle

    Författare :Wei Jiao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Fast synaptic transmission occurs at specialized junctions between neurons referred to as chemical synapses. Action potentials induce an influx of calcium ions into presynaptic terminals, which contain neurotransmitter-filled synaptic vesicles (SVs), triggering fusion of the vesicles with the plasma membrane and resulting in the release of neurotransmitters. LÄS MER

  7. 20. The gamma-tubulin meshwork as a therapeutic target

    Författare :Lisa Lindström; Malmö Molekylär patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gamma-tubulin; retinoblastoma; nuclear formation; meshwork; mitochondria; homeostasis;

    Sammanfattning : Cancer is a heterogeneous disease and treatment regime is dependent on type and location of the tumor. Several of the commonly used chemotherapeutics target the functions of the microtubules. One of the major problems with these drugs is the adverse effects associated with their use. LÄS MER