Sökning: "Fluorescence spectrometry"

Visar resultat 1 - 5 av 54 avhandlingar innehållade orden Fluorescence spectrometry.

  1. 1. Biomarker detection via lab-on-a-chip integrated immunoaffinity approach for fluorescence and mass spectrometry readout

    Författare :Asilah Ahmad Tajudin; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; immunoaffinity; affinity prefractionation; immunoMALDI; solid-phase extraction; protein digestion; ISET; antibody microarray; signal amplification; fluorescence; microfluidics; lab on a chip; separation; acoustophoresis; ultrasound; acoustic radiation force; plasma; proteomics; MALDI mass spectrometry; immunoassay; porous silicon.;

    Sammanfattning : The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. LÄS MER

  3. 2. Methods for elucidating membrane protein structure and function

    Författare :Carolina Trkulja; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; patch clamp; antibodies; mass spectrometry; ion channels; proteomics; fluorescence; TRPV1; cholesterol.; limited proteolysis; Membrane proteins;

    Sammanfattning : Elucidation of the structure-function relationship of membrane proteins increases our understanding of many biological processes, both physiological and pathological. However, membrane proteins have been notoriously difficult to study, having part of their structure embedded into the lipid cell membrane. LÄS MER

  4. 3. Molecular-level dissolved organic matter dynamics in lakes : Constraints on reactivity and persistence

    Författare :Anne Marie Kellerman; Lars J. Tranvik; Dolly N. Kothawala; Thorsten Dittmar; Robert G. M. Spencer; Uppsala universitet; []
    Nyckelord :dissolved organic matter; DOM; dissolved organic carbon; organic matter characterization; fluorescence; PARAFAC; molecular weight; mass spectrometry; FT-ICR-MS; boreal lakes; Biology with specialization in Limnology; Biologi med inriktning mot limnologi;

    Sammanfattning : Dissolved organic matter (DOM) is a central component of the global carbon cycle. Thus, small changes to the amount of DOM imported, processed and produced within lakes can have a large effect on regional carbon budgets. In addition to being a vital energy source at the base of the aquatic food web, DOM is physico-chemically reactive. LÄS MER

  5. 4. On methods for probing structure and function of membrane proteins

    Författare :Erik Jansson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; proteomics; patch-clamp; mass spectrometry.; proteoliposomes; microfluidic superfusion; cholesterol; TRPV1; limited proteolysis; Membrane proteins; fluorescence;

    Sammanfattning : The determination of structure–function relationships in membrane proteins plays a key role for the understanding of molecular mechanisms in biological systems, and may provide information on how these systems can be modulated by pharmaceuticals. The aim of the work described herein was to develop methods for studying structure and function of membrane proteins, ideally in combination. LÄS MER

  7. 5. X-ray Fluorescence Spectrometry for Environmental Applications

    Författare :Siwen An; Göran Thungström; Börje Norlin; Richard Brenner; Mittuniversitetet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Heavy metal contamination in environmental applications is particularly important because of its potential impact on associated ecosystems and human health. At present, monitoring of heavy metals is usually done by taking and preparing samples for off-line laboratory measurements. LÄS MER