Sökning: "antibody microarray"

Visar resultat 1 - 5 av 49 avhandlingar innehållade orden antibody microarray.

  1. 1. On the analysis of antibody repertoires

    Författare :August Jernbom Falk; Peter Nilsson; Anna Månberg; Albert J.R. Heck; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody repertoire; autoantibodies; serology; microarray; bead array; affinity proteomics; psychosis; SARS-CoV-2; COVID-19; post-COVID-19 condition; immunoglobulin; IgG; Biotechnology; Bioteknologi;

    Sammanfattning : The antibody repertoire is the ensemble of antibodies found in an individual at a given time. It displays high heterogeneity between individuals while being both largely temporally stable within an individual and rapidly responsive to immunological challenge. LÄS MER

  3. 2. Strategies for Miniaturized Biomarker Detection

    Författare :Belinda Adler; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomarker; miniturization; lab-on-a-chip; proteomics; PSA; microarray; mass spectrometry; MALDI MS; SPE; sample preparation; immunoaffinity; antibody; aptamer; mass tag; ISET.;

    Sammanfattning : The aim of this thesis is development and application of different miniaturized strategies for detection of biomarkers. The biomarker PSA (prostate specific antigen), which is prostate cancer specific, has been the main focus of the thesis. LÄS MER

  4. 3. Synthetic Paper for Point-of-Care Diagnostics : Capillary control, surface modifications, and their applications

    Författare :Weijin Guo; Wouter van der Wijngaart; Jonas Hansson; Govind V. Kaigala; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; capillary pump; lateral flow test; synthetic paper; OSTE; microarray; point-of-care; surface energy; viscosity; enrofloxacin; plasma separation; protein recovery rate; agglutination; antibody; glass; nitrocellulose; hydrophilic treatment; click chemistry; thiol-yne; thiol-maleimide; biotin-streptavidin; kapillärpump; lateral flödesprov; syntetiskt papper; OSTE; mikroarray; point-of-care; ytenergi; viskositet; enrofloxacin; plasmaseparation; proteinåtervinningshastighet; agglutination; antikropp; glas; nitrocellulosa; hydrofil behandling; klickkemi; tiol-yne; tiol-maleimid; biotin-streptavidin; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : Capillary-based platforms for diagnostics are popular for the point-of-care diagnostics market because of their low cost, easy fabrication, and easy operation. Lateral flow tests are an excellent example of capillary-based platforms for point-of-care diagnostics. LÄS MER

  5. 4. Bioimaging for analysis of protein expression in cells and tissues using affinity reagents

    Författare :Emma Lundberg; Torbjörn Gräslund; Mathias Uhlén; Rainer Pepperkok; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Affibody; antibody; biomarker; cell line; cell microarray; colorectal cancer; confocal microscopy; HER2; immunohistochemistry; immunofluorescence; light microscopy; protein expression; protein localization; SATB2; tissue microarray; Bioengineering; Bioteknik; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The detection and analysis of biomolecules, such as proteins, are of great interest since these molecules are fundamental for life and our health. Due to the complexity of biological processes, there is a great advantage of studying proteins in their natural context, for example by using bioimaging. LÄS MER

  7. 5. Generation and characterization of antibodies for proteomics research

    Författare :Karin Larsson; Sophia Hober; John McCafferty; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody; antibody validation; immunohistochemistry; immunofluorescence; tissue microarray; Western blot; epitope mapping; antigen design; Bioengineering; Bioteknik;

    Sammanfattning : Specific antibodies are invaluable tools for proteomics research. The availability of thoroughly validated antibodies will help to improve our understanding of protein expression, localization and function; fundamental processes and features of all living organisms. LÄS MER