Sökning: "cannabinoid"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet cannabinoid.

  1. 1. Cannabinoids as neuroprotective agents a mechanistic study

    Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskap

    Författare :Olov Nilsson; Umeå universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cannabinoid; neuroprotection; inflammation; cytokine; neutrophil; MEDICINE Physiology and pharmacology Pharmacological research Pharmacology; MEDICIN Fysiologi och farmakologi Farmakologisk forskning Farmakologi;

    Sammanfattning : Glucose and oxygen supply to the brain is critical for its proper function and when it is restricted as during a stroke, neurons and glial cells quickly become necrotic leading to structural damage as well as functional impairment and even death. To date there are few effective therapies that inhibit the neurodegenerative process and improves the outcome for the affected individual. LÄS MER

  2. 2. Pharmacology of Palmitoylethanolamide and Related Compounds

    Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskap

    Författare :Kent-Olov Jonsson; Umeå universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anandamide; cannabinoid; FAAH; palmitoylethanolamide; palmitoylisopropylamide; inflammation; mast cells; Farmakologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. LÄS MER

  3. 3. Synthesis of bioactive natural products and analogues

    Detta är en avhandling från Department of Chemistry, Lund University

    Författare :Dan Killander; Lund University.; Lunds universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAR; natural product; total synthesis; benzochromene; fluorene; cannabinoid; statin; TRPA1; TSLP; antiprotozoal; nociception; asthma; inflammation;

    Sammanfattning : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. LÄS MER

  4. 4. Studies of cannabinoid receptor 1 in mantle cell lymphoma

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Laboratory Medicine

    Författare :Kristin Gustafsson; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects older individuals and has a male predominance. MCL has one of the worst prognoses among lymphomas and currently there is a search for a curative therapy. LÄS MER

  5. 5. Development of cannabinoid subtype-1 (CB1) receptor ligands for PET

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Författare :Sean R Donohue; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Introduction. Abnormalities in brain cannabinoid subtype-1 (CB1) receptor concentrations and/or signaling pathways may be involved in a variety of psychiatric and neurodegenerative disorders. There is a strong need to image and quantify brain CB1 receptor concentrations in living humans under baseline and diseased conditions. LÄS MER