Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet cannabinoid.
Sammanfattning : Glucose and oxygen supply to the brain is critical for its proper function and when it is restricted as during a stroke, neurons and glial cells quickly become necrotic leading to structural damage as well as functional impairment and even death. To date there are few effective therapies that inhibit the neurodegenerative process and improves the outcome for the affected individual. LÄS MER
Sammanfattning : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. LÄS MER
Sammanfattning : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. LÄS MER
Sammanfattning : Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects older individuals and has a male predominance. MCL has one of the worst prognoses among lymphomas and currently there is a search for a curative therapy. LÄS MER
Sammanfattning : Introduction. Abnormalities in brain cannabinoid subtype-1 (CB1) receptor concentrations and/or signaling pathways may be involved in a variety of psychiatric and neurodegenerative disorders. There is a strong need to image and quantify brain CB1 receptor concentrations in living humans under baseline and diseased conditions. LÄS MER