Sökning: "Endopeptidase"

Visar resultat 6 - 10 av 24 avhandlingar innehållade ordet Endopeptidase.

  1. 6. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    Författare :Caroline Sandén; Drug Target Discovery; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER

  3. 7. Biogas Production from Citrus Wastes and Chicken Feather : Pretreatment and Co-digestion

    Författare :Gergely Forgács; Högskolan i Borås; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; anaerobic digestion; pretreatments; co-digestion; economic analyses; citrus wastes; feather; Energi; material; Resursåtervinning; Resource Recovery;

    Sammanfattning : Anaerobic digestion is a sustainable and economically feasible waste management technology, which lowers the emission of greenhouse gases (GHGs), decreases the soil and water pollution, and reduces the dependence on fossil fuels. The present thesis investigates the anaerobic digestion of waste from food-processing industries, including citrus wastes (CWs) from juice processing and chicken feather from poultry slaughterhouses. LÄS MER

  4. 8. Design and stereoselective syntheses of Phe-Phe dipeptidomimetics

    Författare :Annika Jenmalm Jensen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Sammanfattning : Several stereochemically well characterized Phe-Phe dipeptidomimetics have been designed and synthesized. The Phe-Phe vinyl isostere was used as a key intermediate. The synthesized series of mimetics includes two isomeric epoxides, four 1,2-dihydroxyethylene isomers, two isomeric allylic alcohols and two isomeric allylic fluorides. LÄS MER

  5. 9. Cell wall remodeling proteins in Mycobacterium tuberculosis : structure, function and inhibition

    Författare :Eva Maria Rebrova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The complex and peculiar cell wall architecture is vital for the survival of M. tuberculosis in the host and therefore an established target for several currently used drugs. LÄS MER

  7. 10. The Impact of Substance P (SP) N-Terminal Metabolite SP1-7 in Opioid Tolerance and Withdrawal

    Författare :Qin Zhou; Tsukasa Sakurada; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Sammanfattning : The heptapeptide SP1-7, a metabolite of the neuroactive peptide substance P (SP), is suggested to play a role in opioid addiction and memory function. These two dimensions are known to involve dopamine and glutamate transmissions mediated through dopamine receptors and N-methyl-D- aspartate (NNMA) receptors, respectively. LÄS MER