Sökning: "Endopeptidase"

Visar resultat 16 - 20 av 24 avhandlingar innehållade ordet Endopeptidase.

  1. 16. Galanin : Studies by Modification of the Ligand and the Receptor

    Författare :Anders Juréus; Claes-Göran Östeson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Other chemistry; Övrig kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. LÄS MER

  3. 17. Increasing the interpretability of Alzheimer-related biomarkers: cell- and cerebrospinal fluid-based studies with focus on neurogranin

    Författare :Faisal Hayat Nazir; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; neurogranin; APP; human iPSCs; CSF;

    Sammanfattning : Biomarkers for Alzheimer’s disease (AD) is a growing field of research. A particularly vibrant field during recent years has been biomarkers for synaptic dysfunction. LÄS MER

  4. 18. Opioids in the management of pain during delivery

    Författare :Christina Olofsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Labour pain; systemic opioids; analgesia; epidural; subarachnoid; sufentanll; fentanyl; postpartal urinary retention; caesarean section; cerebrospinal fluid; endogenous pain controlling mechanisms;

    Sammanfattning : Labour and delivery involve severe pain for most women. The goal for pain treatment in obstetrics is to provide effective and safe analgesia during all phases of delivery. The ideal method for pain relief during delivery is not yet available. LÄS MER

  5. 19. Analysis of new biomarkers and their kinetics in connection with ST-elevation myocardial infarction and percutaneous coronary intervention

    Författare :Rahel Befekadu Wodajo; Sofia Ramström; Magnus Grenegård; Anders Larsson; Dick Wågsäter; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STEMI; PTX3; sTNFR1; sTNFR2; Cathepsin S; MASP-1 AT MASP-1 C1-INH; MASP-2 AT; MASP-2 C1-INH;

    Sammanfattning : This thesis studies different biomarkers in a cohort of patients suffering from ST-elevation myocardial infarction (STEMI) who underwent Percutaneous coronary intervention (PCI) in Örebro in 2011-2012. Blood samples were collected at three time points, at the arrival at the hospital, 1-3 days after PCI and for a smaller group of patients also 3 months after PCI. LÄS MER

  7. 20. Studies on the level of substance P and calcitonin gene-related peptide in cerebrospinal fluid of pregnant women and patients with chronic pain and in rat brain after spinal cord injury : Special reference to analytical aspects of neuropeptides

    Författare :Zhurong Liu; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Substance P; Calcitonin gene-related peptide; Radioimmunoassay; High performance liquidchromatography; Cerebrospinal fluid and chronic pain; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Sammanfattning : Substance P (SP) and calcitonin gene-related peptide (CGRP) are sensory peptides known to be involved innociception and inflammatory processes. It is well demonstrated that the two peptides can be released from spinal cord neurons during inflammation and chronic pain induced by peripheral nerve injury. LÄS MER