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1. Elongation factor 2: A key component of the translation machinery in eukaryotes : Properties of yeast elongation factor 2 studied in vivo
Sammanfattning : Synthesis of proteins is performed by the ribosome, a large ribonucleoprotein complex. Apart from the ribosome, numerous protein factors participate in this process. Elongation factor 2 (eEF2) is one of these factors. eEF2 is an essential protein with a mol. LÄS MER
2. The eukaryotic protein synthesis elongation cycle : structure and function of the elongation factor 2
Sammanfattning : .... LÄS MER
3. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting
Sammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER
4. Ribosomal proteins L5, L15 and elongation factor 2, three vital components of the translation machinery : Functional features of RPL5, RPL15 and EF2 from Saccharomyces cerevisiae studied in vivo
Sammanfattning : Protein synthesis is an essential, energy consuming and tightly regulated process in all living cells. A central core of the cellular protein-factory is a macromolecule called ribosome. Ribosomes are composed of ribosomal RNAs (rRNAs) and proteins (RPs). Additional components such as elongation factors (EFs) also contribute to this process. LÄS MER
5. Regulation of protein synthesis in eukaryotes : control of elongation factor 2 phosphorylation
Sammanfattning : .... LÄS MER