Sökning: "Early-onset"
Visar resultat 21 - 25 av 193 avhandlingar innehållade ordet Early-onset.
21. Stretch-shortening cycle (SSC) muscle power, muscle strength and functional capacity in Scandinavian women and men - Effects of ageing
Sammanfattning : Ageing is associated with a gradual decline in physical function due to age-related loss of muscle mass, strength, and muscle power, leading to loss of independence. Physical therapists employ various tests to assess of physical functional performance, postural control, and muscle strength. LÄS MER
22. Genetic Studies of Alzheimer's Disease
Sammanfattning : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. LÄS MER
23. Translating Cardiac and Cardiometabolic GWAS Using Zebrafish
Sammanfattning : Genome-wide association studies (GWAS) have identified thousands of loci associated with cardiac and cardiometabolic traits. However, the trait-associated variants usually do not clearly point to causal gene(s), mechanism(s) or tissue(s). Model systems that allow for a comprehensive and quick candidate gene screening are necessary, ideally in vivo. LÄS MER
24. Genetic polymorphism and breast cancer risk in young women
Sammanfattning : Breast cancer is the most common malignancy among women in the western world. Although the disease is rare in young women, it is one of the main causes of death at young age. The early onset breast cancer has demonstrated more aggressive pathological features than the late onset disease. LÄS MER
25. Experimental and Clinical Studies of Oxidative Stress in Pre-Eclampsia
Sammanfattning : Impaired placentation and oxidative stress are proposed to play major roles in the pathogenesis of pre-eclampsia (PE). It has recently been pointed out that PE might be more than one disease and may have several different pathogeneses. LÄS MER
