Sökning: "Down´s syndrome"

Hittade 2 avhandlingar innehållade orden Down´s syndrome.

  1. 1. Coeliac Disease: aspects in different child populations

    Författare :Annelie Carlsson; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EMA; Turner´s syndrome; Down´s syndrome; screening; diabetes mellitus; prevalence; coeliac disease; gluten; AGA; endomysium antibodies; IgA-gliadinantibodies; Pediatrics; Pediatri;

    Sammanfattning : The true prevalence of coeliac disease includes patients with symptomatic/diagnosed disease, and silent or undiagnosed disease. The incidence of diagnosed coeliac disease increased steeply in Swedish children born after 1982, when a change in infant feeding recommendations was made. LÄS MER

  2. 2. Chemotherapy in Childhood Acute Lymphoblastic Leukemia : In vitro cellular drug resistance and pharmacokinetics

    Författare :Britt-Marie Frost; Henrik Schröder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; cytotoxicity; drug resistance; pharmacokinetics; Acute lymphoblastic leukemia; childhood; in vitro assay; vincristine; doxorubicin; Down`s syndrome; CHS 828.; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Sammanfattning : The aims of the studies described in this thesis were to investigate the pharmacokinetics of and cellular resistance to chemotherapy as causes of treatment failure in childhood acute lymphoblastic leukemia (ALL).Leukemic cells from 370 children with newly diagnosed ALL were tested by the Fluorometric Microculture Cytotoxicity Assay to measure their resistance to each of ten standard cytotoxic drugs. LÄS MER