Sökning: "Britt-Marie Frost"

Hittade 5 avhandlingar innehållade orden Britt-Marie Frost.

1. 1. Chemotherapy in Childhood Acute Lymphoblastic Leukemia : In vitro cellular drug resistance and pharmacokinetics

   Författare :Britt-Marie Frost; Henrik Schröder; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; cytotoxicity; drug resistance; pharmacokinetics; Acute lymphoblastic leukemia; childhood; in vitro assay; vincristine; doxorubicin; Down`s syndrome; CHS 828.; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

   Sammanfattning : The aims of the studies described in this thesis were to investigate the pharmacokinetics of and cellular resistance to chemotherapy as causes of treatment failure in childhood acute lymphoblastic leukemia (ALL).Leukemic cells from 370 children with newly diagnosed ALL were tested by the Fluorometric Microculture Cytotoxicity Assay to measure their resistance to each of ten standard cytotoxic drugs. LÄS MER

3. 2. Towards Good Palliation for Children with Cancer : Recognizing the Family and the Value of Communication

   Författare :Li Jalmsell; Britt-Marie Frost; Mats Hansson; Jan-Inge Henter; Ulrika Kreicbergs; Steven Joffe; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; palliative care; child; cancer; family; communication; end-of-life care; bereavement; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Pediatric cancer imposes a threat on the child’s life and approximately every fifth child diagnosed with cancer will die due to his or her disease. The overall aim of this thesis was to explore palliative care of children with cancer and bereaved family members. LÄS MER

4. 3. Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia

   Författare :Josefine Palle; Gudmar Lönnerholm; Britt-Marie Frost; Rolf Larsson; Henrik Schröder; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood; acute myeloid leukemia; drug resistance; pharmacokinetics; chromosomal abnormalities; Down syndrome; MLL-rearrangement; t 9; 11 ; Paediatric medicine; Pediatrisk medicin;

   Sammanfattning : Despite major advances in our understanding of the biology of childhood acute myeloid leukemia (AML) and the development of new cytotoxic drugs, the prognosis of long-term survival is still only 60-65 %.In the present research, we studied the pharmacokinetics of drugs used in the induction therapy of childhood AML and performed in vitro drug sensitivity testing of leukemic cells from children with AML. LÄS MER

5. 4. Traditional lime mortar and plaster : Reconstruction with emphasis on durability

   Författare :Kristin Balksten; Tor Broström; Britt-Marie Steenari; Thorborg Konow von; Chalmers Tekniska Högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lime plaster; lime mortar; masonry; craftsmanship; pore structure; frost resistance; historic mortar; Conservation HGO ; Kulturvård HGO ;

   Sammanfattning : Lime mortar and plaster have been investigated with the aim to improve the knowledge on how to make them as durable as before the cement technology was developed. The background was the durability problems experienced for newly produced lime plaster on the medieval churches on the island of Gotland, Sweden. LÄS MER

7. 5. Kalkputs : porstrukturens betydelse för beständighet

   Författare :Kristin Balksten; Tor Broström; Britt-Marie Steenari; Jan-Erik Lindkvist; Chalmers; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; kalkputs; kalkbruk; murning; putsning; hantverk; frostresistens; porstruktur; Conservation HGO ; Kulturvård HGO ;

   Sammanfattning : When restoring historic lime plaster it can be difficult to reach the required durability. Today newly made lime plaster can fall off due to frost damages after only a couple of winters. To understand and solve these problems, the subject has been studied from different perspectives. LÄS MER