Sökning: "Conformational analysis"

Visar resultat 11 - 15 av 145 avhandlingar innehållade orden Conformational analysis.

  1. 11. Deciphering conformational ensembles and communication pathways in biomolecules

    Författare :Annie M. Westerlund; Lucie Delemotte; Erik Lindahl; Kresten Lindorff-Larsen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular dynamics; Clustering; Machine learning; Network analysis; Calmodulin; KCNQ1; Biological Physics; Biologisk fysik;

    Sammanfattning : Life is constructed by small building blocks called cells. Proteins are the biomolecules within these cells which carry out different functions. Proteins located in the cell membrane, for example, allow for the transport of ions and small molecules, as well as communication, across the cell membrane. LÄS MER

  3. 12. Conformational analysis of ribonucleic acids (RNA) by NMR spectroscopy

    Författare :Peter Agback; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 13. Synthesis and conformational analysis of C-glycosidic KDO-analogues

    Författare :Martin Orbe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  5. 14. Synthesis of oligosaccharides and conformational analysis by NMR spectroscopy

    Författare :Jerk Rönnols; Göran Widmalm; Eszter Borbas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : The first part of this thesis describes investigations of the conformations of six N-linked pseudodisaccharides (Paper I), which were synthesized as glycosidase inhibitor candidates, and 10 β-D-xylopyranoside derivatives bearing hydrophobic aglycons (Paper II), by NMR spectroscopic methods. In paper I the ring conformations of 2- and 3-amino-α-D-altropyranosides, and ω torsions of altrosides, glucosides and mannosides were described, in neutral and protonated states. LÄS MER

  7. 15. Autoproteolysis accelerated by conformational strain - a novel biochemical mechanism

    Författare :Denny Johansson; Göteborgs universitet; []
    Nyckelord :SEA domain; autoproteolysis; MUC1; conformational strain; protein folding;

    Sammanfattning : Natural fragmentation of polypeptide chains by autoproteolysis occurs in a number of protein families. It is a vital step in the maturation of several enzymes and in the formation of membrane-associated mucins that constitute a part of the protective mucus barrier lining epithelial cells. LÄS MER