Sökning: "Conformational analysis"

Visar resultat 21 - 25 av 145 avhandlingar innehållade orden Conformational analysis.

  1. 21. Metallocene based peptidomimetics and chiral catalysts

    Författare :Suzana Maricic; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; asymmetric catalysis.; metallocene based amino alcohols; one-pot macrocyclisation; cyclic peptides; Organometallic substance P and Leu 5 -enkephalin; conformational analysis;

    Sammanfattning : Several optically active organometallic Phe-AAn-Phe peptidomimetics and macrocyclic Phe-(Phe)n peptides have been synthesized by either intra- or intermolecular peptide bond formation of the corresponding bis(amino acid) derivatives. The key bis(amino acid) derivatives were available from an improved multi-step synthetic route, utilising Horner-Wadswort-Emmons olefination of organometallic aldehydes with phosphonylglycine reagents, enantioselective hydrogenation of didehydro amino acids and classical solution and/or solid phase peptide synthesis methodology. LÄS MER

  3. 22. Structural and Conformational Analysis of Bacterial Polysaccharides using NMR Spectroscopy

    Författare :Axel Furevi; Göran Widmalm; Corine Sandström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : Carbohydrates is one of the three classes of biomolecules found in nature. It is the most common one in comparison to the other two classes, lipids and proteins. However, this simple categorization does not reflect the reality since carbohydrates often are covalently linked to e.g. LÄS MER

  4. 23. Photoinduced Electron and Energy Transfer in Π-Conjugated Systems

    Författare :Melina Gilbert Gatty; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fs spectroscopy; exciton coupling; conjugated porphyrin oligomers; ps spectroscopy; molecular wire; electron transfer; conformational analysis; self‒assembly; anthracene dendrimers; energy transfer; fluorescence anisotropy;

    Sammanfattning : Photosynthesis is a fascinating process that provides food and oxygen. In this thesis, focus is on understanding and controlling the early processes of photosynthesis, namely photoinduced energy and electron transfer. LÄS MER

  5. 24. Applications of nuclear magnetic resonance spectroscopy in structural and conformational analysis

    Författare :Anne Helander; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 25. Computational Modeling of Macrocycles and Structure-Based Design of Novel Antibacterial Compounds

    Författare :Gustav Olanders; Anders Karlén; Peter Brandt; Christian Sköld; Dan Sindhikara; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrocycles; docking; conformational sampling; conformational prefer-ences; antibiotics;

    Sammanfattning : The integration of computational methods into the drug discovery process provides valuable tools to help advance new and improved drugs into the clinic. As medicinal chemists explore novel targets and new areas of chemical space, our computational toolkit must also evolve. LÄS MER