Sökning: "Censored"

Visar resultat 26 - 30 av 54 avhandlingar innehållade ordet Censored.

  1. 26. Topics on mathematical statistics for medical applications : summary measures and exact simulation of diffusions

    Författare :Celia García-Pareja; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The first part of this thesis deals with exact simulation of multidimensional diffusion processes. The main contribution is the development of an exact rejection algorithm for sampling coupled Wright-Fisher diffusions. The algorithm’s output provides a skeleton from the diffusion sampled at a random number of time points. LÄS MER

  3. 27. Pharmacometric evaluation and improvement of models and study designs - applied in diabetes

    Författare :Moustafa M. A. Ibrahim; Mats O. Karlsson; Maria C. Kjellsson; Paolo Magni; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Pharmacometric models are increasingly used to improve the efficiency of the drug development process and increase our understanding of the studied underlying pathophysiological system. These models require assumptions for handling different types of data and the different model components, and the appropriateness of such assumptions must be carefully inspected for unbiased conclusions. LÄS MER

  4. 28. Statistical analysis and simulation methods related to load-sharing models

    Författare :Patrik Rydén; Yuri Belyaev; Uwe Jensen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Non-parametric and parametric estimation; load-sharing models; asymptotic distribution; martingale; resampling; life testing; reliability;

    Sammanfattning : We consider the problem of estimating the reliability of bundles constructed of several fibres, given a particular kind of censored data. The bundles consist of several fibres which have their own independent identically dis-tributed failure stresses (i.e.the forces that destroy the fibres). LÄS MER

  5. 29. Application of Mixed-Effect Modeling to Improve Mechanistic Understanding and Predictability of Oral Absorption

    Författare :Martin Bergstrand; Mats O Karlsson; Hans Ericsson; Bart Ploeger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Absorption; magnetic marker monitoring; drug release; IVIVC; pharmacometrics; NONMEM; model diagnostics; pcVPC; pvcVPC; visual predictive check; VPC; BQL; paracetamol; sulfapyridine.; Other pharmacy; Övrig farmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Several sophisticated techniques to study in vivo GI transit and regional absorption of pharmaceuticals are available and increasingly used. Examples of such methods are Magnetic Marker Monitoring (MMM) and local drug administration with remotely operated capsules. LÄS MER

  7. 30. Essays on banking, credit and interest rates

    Författare :Kasper Roszbach; Handelshögskolan i Stockholm; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : This dissertation consists of four papers, each with an application of a discrete dependent variable model, censored regression or duration model to a credit market phenomenon or monetary policy question. The first three essays deal with bank lending policy, while the last one studies interest rate policy by Central Banks. LÄS MER