Sökning: "Martin Bergstrand"
Hittade 4 avhandlingar innehållade orden Martin Bergstrand.
1. Application of Mixed-Effect Modeling to Improve Mechanistic Understanding and Predictability of Oral Absorption
Sammanfattning : Several sophisticated techniques to study in vivo GI transit and regional absorption of pharmaceuticals are available and increasingly used. Examples of such methods are Magnetic Marker Monitoring (MMM) and local drug administration with remotely operated capsules. LÄS MER
Sammanfattning : For orally administered drugs, the rate and extent of absorption are governed by the physiology of the gastrointestinal tract, the characteristics of the dosage form and the physico-chemical properties of the drug. This thesis primarily aimed to improve the mechanistic understanding and the predictability of processes involved in the absorption of orally administered drugs using a population modeling approach. LÄS MER
Sammanfattning : The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of these drugs, particularly in vulnerable populations like children and pregnant women. LÄS MER
4. Livsmystik och destruktiv maktsträvan - två poler i Per Olof Sundmans författarskap : en undersökning med särskilt fokus på romanerna Expeditionen och Två dagar, två nätter
Sammanfattning : My thesis addresses the antagonism between the mystery of life and the destructive pursuit of power which forms a central theme in the works of Per Olof Sundman (1922–1992). The purpose is to show that Sundman uses the theme of the encounter/non-encounter and the destructive leader to examine the conditions for allowing a deeper experience of reality and the destructive exercise of power. LÄS MER