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Visar resultat 11 - 15 av 43 avhandlingar som matchar ovanstående sökkriterier.

1. 11. Expression and regulation of water channels and ion transporters : ontogenic aspects

   Författare :Masato Yasui; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :water balance; developmental gene expression regulation; gene transcription; fetal lung fluid; urinary concentrating capacity; hormonal regulation;

   Sammanfattning : The content and distribution of body water changes dramatically during the perinatal period and in infancy. Transport of water across the cell membrane occurs via diffusion and via specific water channels. Transport via water channels is fast and may be hormonally regulated. LÄS MER

3. 12. Functions of Transcriptional Co-regulators in Drosophila development

   Författare :Tobias Lilja; Mattias Mannervik; Ze'ev Paroush; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; Co-regulator; Development; Drosophila; Developmental biology; Utvecklingsbiologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

   Sammanfattning : During Drosophila development, regulation of gene expression through interplay between transcriptional activators and repressors is generating complex patterns of gene expression that leads to cell differentiation. For proper control of transcription, transcription factors bind to DNA at control regions, so called Cis Regulatory Modules (CRM). LÄS MER

4. 13. Mechanisms and improvements of cell transplantation for nerve repair

   Författare :Kai-Hei Tse; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; microporous scaffold; biomaterials; ischemia; cell death; brain derived neurotrophic factor;

   Sammanfattning : Trauma to the nervous system is a frequent clinical problem and new approaches to nerve repair are required. Autologous cell transplantation together with a suitable scaffold material could be used to create a bio-active artificial nerve graft to enhance regeneration. LÄS MER

5. 14. Transcriptional regulation of miRNA-212 and miRNA-132 and their fine-tuning function of beta cell insulin secretion

   Författare :Helena Malm; Diabetes - öcellsexocytos; []
   Nyckelord :;

   Sammanfattning : Type 2 diabetes is characterized by hyperglycemia due to insulin resistance in the target tissue and insufficient insulin secretion from the beta cells. Finding new mechanisms and pathways involved in the regulation of insulin secretion from the pancreatic beta cells is of great importance. LÄS MER

7. 15. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins

   Författare :Ida Nyqvist; Jakob Dogan; Ivarsson Ylva; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Intrinsically disordered proteins; Protein-protein interactions; Disorder-to-order transition; Rate-limiting transition state; Ф-value analysis; NMR relaxation; Side-chain dynamics; Backbone dynamics; Conformational entropy change; Biophysics; biofysik;

   Sammanfattning : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. LÄS MER