Sökning: "CCT oligomer"

Hittade 3 avhandlingar innehållade orden CCT oligomer.

1. 1. The Extended Role of the Molecular Chaperone CCT

   Författare :Andreas Svanström; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; CCT oligomer; Actin; CCT delta; CCT epsilon; Gelsolin; MRTF-A; Cell morphology;

   Sammanfattning : The oligomeric chaperone CCT is a large ATP-dependent chaperonin that consists of two rings placed back-to-back with eight different paralogous subunits with a size of ~ 55 kDa that sit in each of the two rings. The function of CCT is mainly to fold the abundant proteins actin and tubulin, components of the cytoskeleton. LÄS MER

3. 2. The molecular chaperone CCT: Functions beyond folding

   Författare :Josefine Vallin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TRiC; Chaperonin; CCT oligomer; CCT monomer; cancer; p150Glued; gelsolin; STAT3;

   Sammanfattning : The chaperonin-containing tailless complex polypeptide 1 (CCT) is a eukaryotic ~1 MDa barrel shaped molecular chaperone, built up by eight distinct subunits and is required for the folding of the abundant cytoskeletal proteins actin and tubulin. CCT exists as an assembled oligomer, micro-complexes and as individual subunits in the cell. LÄS MER

4. 3. The Chaperonin Containing TCP-1 : Interactions with the Mammalian Cytoskeleton

   Författare :Karen I. Brackley; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular chaperone; Cytoskeleton;

   Sammanfattning : The eukaryotic Chaperonin Containing TCP-1 (CCT) is a heterooligomeric chaperonin essential for enabling the cytoskeletal proteins actin and tubulin to fold to their native state. The eight CCT subunits are encoded by individual genes and are present in cells as the ~960kDa oligomer, as components of micro-complexes, and as monomeric subunits. LÄS MER