Sökning: "Josefine Vallin"

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1. 1. The molecular chaperone CCT: Functions beyond folding

   Författare :Josefine Vallin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TRiC; Chaperonin; CCT oligomer; CCT monomer; cancer; p150Glued; gelsolin; STAT3;

   Sammanfattning : The chaperonin-containing tailless complex polypeptide 1 (CCT) is a eukaryotic ~1 MDa barrel shaped molecular chaperone, built up by eight distinct subunits and is required for the folding of the abundant cytoskeletal proteins actin and tubulin. CCT exists as an assembled oligomer, micro-complexes and as individual subunits in the cell. LÄS MER