Sökning: "C Marcus"

Visar resultat 6 - 10 av 64 avhandlingar innehållade orden C Marcus.

1. 6. Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors Incorporating a P2 Cyclopentane-Derived Scaffold

   Författare :Marcus Bäck; Anja Sandström; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HCV; NS3 protease; Proline mimic; Cyclopentane-derived scaffold; Linear inhibitors; Macrocyclic inhibitors; Organic synthesis; Organisk syntes;

   Sammanfattning : This thesis describes the design, synthesis and structure-activity relationships analysis of potential inhibitors targeting the hepatitis C virus (HCV) NS3 protease. Also discussed is the disease caused by HCV infection and the class of enzymes known as proteases. LÄS MER

3. 7. Design and Synthesis of Inhibitors Targeting the Hepatitis C Virus NS3 Serine Protease and the Aspartic Protease BACE-1

   Författare :Marcus Bäck; Ingemar Kvarnström; Stephen Hanessian; Linköpings universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

   Sammanfattning : This thesis describes the synthesis of molecules designed to inhibit the hepatitis C virus (HCV) NS3 serine protease and the human aspartic protease BACE-1, and it also reports the structure-activity relationships between potential inhibitors and the targeted enzymes. In addition, consideration is given to the class of enzymes known as proteases, as well as the question of why such enzymes can be regarded as suitable targets for developing drugs to combat diseases in general. LÄS MER

4. 8. Macroscopic modelling of coupled multiphysics in swelling cellulose based materials

   Författare :Marcus Alexandersson; Hållfasthetslära; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; multiphysics; multiphase flow; mixture theory; porous media; cellulose based materials; paperboard;

   Sammanfattning : Paperboard has been the basis for packaging materials used to aseptically store and protect food and beverages for a long time. To ensure that there are no bacteria that can spoil the product, sterilizing treatments are made. LÄS MER

5. 9. Evasion of CO₂ from streams : quantifying a carbon component of the aquatic conduit in the boreal landscape

   Författare :Marcus Wallin; Robert Striegl; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Lateral export of carbon (C) from soils to running waters is a persistent pathway for C with terrestrial origin. This "aquatic conduit" might be especially important in boreal regions where a significant part of the global C stock is stored in the soil. LÄS MER

7. 10. Femtosecond Dynamics and Photochemistry in Solution

   Författare :Marcus Rasmusson; Kemisk fysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry; cross-correlation function; chloroiodomethane; dihalides; bromobenzene; ion pairs; solvation; vibrational relaxation; charge-transfer; tetranitromethane; electron transfer; femtosecond spectroscopy; dissociation; Photochemistry; Fotokemi; Chemical technology and engineering; Kemiteknik och kemisk teknologi;

   Sammanfattning : The reaction dynamics of several polyatomic systems have been investigated in solution by femtosecond spectroscopy. Tetranitromethane-naphtalene complexes excited in the charge-transfer band at 400 nm undergo dissociative electron transfer, resulting in three primary products: [naphthalene].+, NO2 and C(NO2)3-. LÄS MER