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Visar resultat 6 - 10 av 44 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. Molecular Characterization of Bladder Cancer Subtypes

    Författare :Pontus Eriksson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder Cancer; Urothelial Carcinoma; Molecular Subtypes; Genomic Characterization; Gene Expression;

    Sammanfattning : Bladder cancer is one of the most common malignancies world-wide, and in Sweden approximately 3000 cases are diagnosed annually. Even though bladder cancer is so common there is low public awareness of the disease, and it has historically been less studied compared to other common types of cancer. LÄS MER

  3. 7. Urinary Bladder Carcinoma – Studies of Outcome of Current Management and Experimental Therapy

    Författare :Truls Gårdmark; Per-Uno Malmström; Jörgen Carlsson; Sverker Hellsten; Willem Oosterlinck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bladder; Epidemiology; Administration; Intravesical; Radiotherapy; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : The thesis concerns the epidemiology, current and possible future treatment of urothelial cancer of the urinary bladder. The Swedish National Quality Registry for Bladder Cancer 1997-2001 was used to explore epidemiology, current therapies and outcome. More common in men, the incidence for Ta and T1 tumours peaks in the age range 70-79 years. LÄS MER

  4. 8. Cancer Immunotherapy : A Preclinical Study of Urinary Bladder Cancer

    Författare :Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; Uppsala universitet; []
    Nyckelord :Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Sammanfattning : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. LÄS MER

  5. 9. Epigenetic and Phenotypic Profiling of Urothelial Carcinoma

    Författare :Mattias Aine; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; DNA methylation; gene expression; urothelial carcinoma; bladder cancer;

    Sammanfattning : Precise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. LÄS MER

  7. 10. Urinary bladder carcinoma, preclinical and clinical studies on EGFR based targeting

    Författare :Peter Bue; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; urinary bladder carcinoma; epidermal growth factor-dextran; radionuclide therapy; Kirurgi; Surgery; Kirurgi; kirurgi; särskilt urologi; Urology;

    Sammanfattning : Radical cystectomy with bilateral pelvic lymphadenectomy is the standard treatment for muscle-invasive transitional cell carcinoma of the urinary bladder. Despite presumably localised malignancies and efficacious management about 50% of patients will die within 5 years, the majority due to metastatic disease. LÄS MER