Sökning: "IL2"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet IL2.

  1. 1. Cancer Immunotherapy : A Preclinical Study of Urinary Bladder Cancer

    Författare :Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; Uppsala universitet; []
    Nyckelord :Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Sammanfattning : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. LÄS MER

  3. 2. Genetic linkage and association studies in celiac disease: discoveries from whole genome analysis

    Författare :Svetlana Adamovic; Göteborgs universitet; []
    Nyckelord :Celiac Disease; genome-wide scan; linkage; association; GWAS; complex disease; autoimmune; 5q31-33; HLA; IL2 IL21;

    Sammanfattning : Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life-long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). LÄS MER

  4. 3. Regulatory function of homeobox genes in the development of C. elegans

    Författare :Yong-Guang Tong; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The nematode worm Caenorhabditis elegans has been widely used as a genetic model for over 40 years to investigate developmental control genes. In this thesis, I studied the roles of several homeobox genes and a novel RNA binding protein (RBD) in the development of C. elegans to understand the function of these genes in higher organisms. LÄS MER

  5. 4. Feeding Lactobacillus paracasei ssp. paracasei strain F19 to infants during weaning : effects on adaptive immunity and gut microbial function

    Författare :Christina West; Olle Hernell; Marie-Louise Hammarström; Outi Vaarala; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adaptive immunity; allergy; complementary food; eczema; gut microbiota; infections; probiotics; short-chain fatty acids; Th1 Th2; weaning; Paediatric medicine; Pediatrisk medicin;

    Sammanfattning : Introduction: Gut microbial composition has been associated with immune-mediated diseases. Breastfeeding yields a microbiota rich in bifidobacteria and promotes colonization by lactobacilli. Bifidobacteria and lactobacilli are considered health-promoting and are used as probiotics, i.e. LÄS MER

  7. 5. New strategies for allogeneic hematopoietic stem cell transplantation with umbilical cord

    Författare :Jens Gertow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Umbilical cord blood is enriched in hematopoietic stem cells. For this reason, cord blood units may be utilized for allogeneic hematopoietic stem cell transplantations when no adult human leukocyte antigen (HLA)‐matched donor is found. LÄS MER