Sökning: "Biochemistry with Emphasis on Theoretical Chemistry"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden Biochemistry with Emphasis on Theoretical Chemistry.

  1. 6. Biological data exchange and the discovery of new protein families in metagenomic samples

    Författare :David N. Messina; Erik Sonnhammer; Miguel Andrade; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : The rise in sequence data has brought both challenges to the way we exchange biological information and opportunities to discover new protein families, primarily through the investigation of uncultured metagenomic samples.The Distributed Annotation System, or DAS, provided a means for exchanging protein sequence data, but there were no open source, stand-alone DAS clients optimized for integrating and viewing these data. LÄS MER

  3. 7. Network and gene expression analyses for understanding protein function

    Författare :Oliver Frings; Erik Sonnhammer; Rune Linding; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological networks; network inference; network analysis; clustering; network module; network crosstalk; expression analysis; gene signature; biomarker; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. LÄS MER

  4. 8. The relationship between orthology, protein domain architecture and protein function

    Författare :Kristoffer Forslund; Erik Sonnhammer; Cristina Al-Khalili Szigyarto; Sarah Teichmann; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; homology; orthology; paralogy; gene duplications; protein function prediction; low-complexity regions; protein domains; domain architecture evolution; introns; intron position conservation; orthology conjecture; domain grammar hypothesis; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. LÄS MER