Sökning: "network module"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden network module.

  1. 1. Network and gene expression analyses for understanding protein function

    Författare :Oliver Frings; Erik Sonnhammer; Rune Linding; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological networks; network inference; network analysis; clustering; network module; network crosstalk; expression analysis; gene signature; biomarker; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. LÄS MER

  3. 2. Omic Network Modules in Complex diseases

    Författare :Tejaswi Venkata Satya Badam; Mika Gustafsson; Zelmina Lubovac-Pilav; Maja Jagodic; Sergio Baranzini; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Biological systems encompass various molecular entities such as genes, proteins, and other biological molecules, including interactions among those components. Understanding a given phenotype, the functioning of a cell or tissue, aetiology of disease, or cellular organization, requires accurate measurements of the abundance profiles of these molecular entities in the form of biomedical data. LÄS MER

  4. 3. Evaluation of Modular Thermally Driven Heat Pump Systems

    Författare :Corey Blackman; Eva Thorin; Chris Bales; Christian Schweigler; Mälardalens universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; sorption heat pump; sorption module; thermochemical energy storage; artificial neural network; built environment; solar energy; gas-driven heat pump; solar cooling; heating and cooling; renewable energy; energy efficiency; experimental; simulation; analytical; Energy- and Environmental Engineering; energi- och miljöteknik; Reesbe företagsforskarskola;

    Sammanfattning : The building sector accounts for approximately 40% of primary energy use within the European Union, therefore reductions in the energy use intensity of this sector are critical in decreasing total energy usage. Given that the majority of energy used within the built environment is for space conditioning and domestic hot water preparation, prudence would suggest that decreasing primary energy used for these end purposes would have the biggest overall environmental impact. LÄS MER

  5. 4. A genomic approach to smooth muscle differentiation and diversity

    Författare :Sven Nelander; Göteborgs universitet; []
    Nyckelord :Keywords: smooth muscle; phenotype; transcriptional regulation; differentiation; transcriptome; microarray; computational prediction; co-expression network; regulatory sequence analysis; gene module; gene battery;

    Sammanfattning : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. LÄS MER

  7. 5. Network-based biomarker discovery for multiple sclerosis

    Författare :Julia Åkesson; Mika Gustafsson; Zelmina Lubovac-Pilav; Lukas Käll; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Complex autoimmune diseases, such as multiple sclerosis (MS), develop as a result of perturbations in the regulatory system controlling the function of immune cells. The disease course of MS is heterogeneous but is characterised by chronic inflammation in the central nervous system causing neurodegeneration resulting in gradual disability worsening. LÄS MER