Sökning: "Bioanalytical sensing"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Bioanalytical sensing.

  1. 1. Advanced Nanofabrication for Novel Plasmonic Biosensors

    Författare :Francesco Mazzotta; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Photo diode; Localized surface plasmon resonance; Bioanalytical sensing; Nanopores.; Solar cell; Nanofabrication; Nanodisks; Nanoplasmonics; Biosensor;

    Sammanfattning : There is an increasing interest in the development of novel biosensors in the foreseeable future.The impact on society of diseases connected to the aging of population, for example infectiousdiseases, cancer and Alzheimer’s disease, has the potential of increasing the running costs ofwelfare over a sustainable threshold already within a few years. LÄS MER

  3. 2. From single-molecule sensing to extracellular vesicles in glioma cells under stress

    Författare :Virginia Claudio; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteome; single molecule sensing; nanoplasmonics; surface plasmon resonance; exosomes; glioblastoma; extracellular vesicles; cellular stress; lipid composition;

    Sammanfattning : This thesis describes the work I conducted in two different areas, namely biomolecular sensing and quantitative cell biology. The work in the former area was focused on the optimization of plasmonic metamaterials for sensing applications, and in the latter on the characterization of extracellular vesicles released by glioblastoma cells under stress conditions. LÄS MER

  4. 3. Polypeptide functionalized gold nanoparticles for bioanalytical applications

    Författare :Robert Selegård; Bo Liedberg; Karin Enander; Daniel Aili; Wilhelm Robert Glomm; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Detection strategies that allow for simple, rapid, cost efficient and sensitive monitoring of proteins and their interactions with biomolecules are of great importance in drug development and diagnostics. This thesis describes the development of bioanalytical applications based on the tunable self-assembly of gold nanoparticles functionalized with a de novo designed polypeptide. LÄS MER

  5. 4. Characterization of biological nanoparticles using evanescent field sensing

    Författare :Mattias Sjöberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; label-free; protein corona; mass quantification.; liposomes; single-particle; SPR; Waveguide scattering microscopy;

    Sammanfattning : In light of the increasingly realized importance of nanoparticle-based biological processes, in biology as well as in technological applications, there is a need of analysis methods capable of accurately quantifying different characteristics and processes involving these elusive entities. The aim of this thesis is the development and utilization of surface-based bioanalytical sensing methods for quantitative characterization of biological nanoparticles, most of which being based on surface-confined evanescent-field illumination. LÄS MER

  7. 5. Multiparametric Optical Characterization of Biological Nanoparticles using Evanescent Field Sensing

    Författare :Mattias Sjöberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein corona; single-particle; liposomes; SPR; lipid nanoparticles; Waveguide scattering microscopy; label-free; mass quantification.;

    Sammanfattning : In light of the increasingly realized dependence of many biological functions on nanoscopic supramolecular assemblies, also including novel biotechnological applications, there is a need for advanced analysis methods capable of accurately quantifying different characteristics of these elusive entities. The prime aim of this thesis is the development and utilization of surface-based bioanalytical sensing methods for quantitative characterization of biological nanoparticles. LÄS MER