Sökning: "Target enrichment"

Visar resultat 1 - 5 av 84 avhandlingar innehållade orden Target enrichment.

1. 1. Amino acid sequence and side chain specific synthetic receptors targeting protein phosphorylation

   Författare :Anil Incel; Frank Kjeldsen; Malmö universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; imprinted polymers; synthetic receptors; PTM; phosphorylation; enrichment; diagnosis;

   Sammanfattning : Antibodies have become a critical component of many diagnostic assays and are used for therapeutic purposes. Nevertheless they often fail to meet the strict performance demands raised in industry and in the clinic (e.g. stability, reproducibility, selectivity, affinity). LÄS MER

3. 2. Tagging systems for sequencing large cohorts

   Författare :Mårten Neiman; Afshin Ahmadian; Peter Savolainen; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; Genetics; Genetik;

   Sammanfattning : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. LÄS MER

4. 3. The age of museomics : How to get genomic information from museum specimens of Lepidoptera

   Författare :Elsa Call; Biodiversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Museomics; Museum specimens; Lepidoptera; WGS; Target enrichment; Phylogenomics; NGS;

   Sammanfattning : In the age of museomics, the ability to sequence the genetic material from old museum specimens provides an invaluable and often untapped molecular resource. The application of the latest Next-Generation sequencing (NGS) technologies to such specimens allows us to utilise the diverse biobank that is natural history museums. LÄS MER

5. 4. The CD40 Receptor - Target,Tool and Technology

   Författare :Peter Ellmark; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; SPIRE; mammalian; library; cDNA; selection; receptor revision; phage display; scFv; human; CD40; antibodies;

   Sammanfattning : CD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. LÄS MER

7. 5. Enrichment and Separation of Phosphorylated Peptides on Titanium Dioxide Surfaces : Applied and Fundamental Studies

   Författare :Anna I. K. Eriksson; Anders Hagfeldt; Katarina Edwards; Victor Agmo Hernández; Hubert Girault; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Posttranslational modification; Phosphorylation; Mass spectrometry; MALDI; Adsorption; QCM-D; Physical Chemistry; Fysikalisk kemi;

   Sammanfattning : Protein phosphorylation is a very common posttranslational modification (PTM), which lately has been found to hold the keyrole in the development of many severe diseases, including cancer. Thereby, phosphoprotein analysis tools, generally based on specific enrichment of the phosphoryl group, have been a hot topic during the last decade. LÄS MER