Sökning: "BALB c mice"

Visar resultat 16 - 20 av 51 avhandlingar innehållade orden BALB c mice.

1. 16. Influence of Ly49 inhibitory receptors and MHC class I on T cell and NK cell function

   Författare :Linda Öberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :NK cell; T cell; Ly49; MHC class I;

   Sammanfattning : Natural Killer cells (NK) can kill virus infected cells and tumor cells but do not harm normal surrounding cells. The function of Ly49 receptors on NK cells is important in maintaining selftolerance since they transmit inhibitory signals when bound to endogenous MHC class I molecules. Their role in T cells is however unclear. LÄS MER

3. 17. Type 1 diabetes : the autoimmune process and islet transplantation

   Författare :Stella Jacobson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Type 1 diabetes (T1D) is an autoimmune disease characterized by the selective loss of the insulin-producing β-cells residing in the islets of Langerhans in the pancreas. Cytokines are involved in diabetes development in the nonobese diabetic (NOD) mouse model. LÄS MER

4. 18. B cell deviations and type 1 diabetes in the NOD mouse

   Författare :Mia Sundström; Kristina Lejon; Susanna Cardell; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type 1 diabetes; Autoimmunity; NOD mouse; Idd; TACI; Immune response; Immune complex; immunologi; Immunology;

   Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. LÄS MER

5. 19. Heavy metal-induced activation of the murine immune system and autoimmunity : a comparative study of mercury and silver

   Författare :Uno Johansson; Klas Nordlind; Östergötlands Läns Landsting; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The activation and proliferation ofT- and B-cells induced by treatment with mercuric chloride (HgC12) or silver·nitrate (AgN03) was studied in mouse strains genetically susceptible (SJL, A. SW, A.TH, BALE/C) or resistant (A.TL, BALB. LÄS MER

7. 20. The Perfect Storm? Gluten and type 1 diabetes

   Författare :Emma Adlercreutz; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKG2D; Celiac disease autoimmunity; Gluten; Type 1 diabetes; Perinatal risk;

   Sammanfattning : Aim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk markers and autoantibodies associated with type 1 diabetes and celiac disease during the first year after diagnosis of type 1 diabetes; to investigate the effect of gluten on the risk of developing type 1 diabetes; to evaluate the impact of perinatal factors on the risk of developing both type 1 diabetes and celiac disease. LÄS MER