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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Eosinophil Inflammation in Allergic Disease : Clinical and experimental studies in allergic asthma and allergic rhinitis

    Författare :Mary Kämpe; Marie Carlson; Christer Janson; Gunnemar Stålenheim; Magnus Sköld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allergic asthma; allergic rhinitis; eosinophils; pollen season; bronchial challenge; nasal challenge eosinophil degranulation; PI3K signalling; Allergology; Allergologi; Lung Medicine; Lungmedicin; Lung Medicine; Lungmedicin;

    Sammanfattning : Allergic diseases are chronic inflammatory conditions, characterised by eosinophil inflammation systemically and in target organs, where cytotoxic granule proteins are responsible for tissue injury. Allergic rhinitis is known to be a risk factor for the development of asthma, yet not all with rhinitis develop asthma. LÄS MER

  3. 2. In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy

    Författare :Khosro Masjedi; Marita Troye-Blomberg; Niklas Ahlborg; Lone Skov; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ELISpot; contact allergy; parthenolide; methylisothiazolinones; nickel; hapten; Allergology; Allergologi; immunologi; Immunology;

    Sammanfattning : Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to metal ions. LÄS MER

  4. 3. Eczema in young children : aspects of clinical investigation and treatment

    Författare :Gunilla Norrman; Karin Fälth-Magnusson; Magnus Borres; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergy; eczema; skin tests; food allergy; food challenge; IgG4; IgE; elimination diet; SCORAD; children; infants; adolescents; Allergology; Allergologi;

    Sammanfattning : Bakgrund: Eksem förekommer hos 10-20% av barn i hela världen. En tredjedel av barnen med eksem har födoämnesallergi. Hos de flesta växer födoämnesallergin bort innan skolåldern. Förbättrat kliniskt omhändertagande och bättre förståelse av hur klinisk tolerans uppkommer är viktiga mål för forskning inom barnmedicin. LÄS MER

  5. 4. Novel Bioinformatics Applications for Protein Allergology, Genome-Wide Association and Retrovirology Studies

    Författare :Álvaro Martínez Barrio; Erik Bongcam-Rudloff; Teresa K Attwood; Uppsala universitet; []
    Nyckelord :data integration; web services; protein allergology; risk assessment; cross reactivity; endogenous retroviruses; ERV; dog; canine; GWAS; genome-wide association studies;

    Sammanfattning : Recently, the pace of growth in the amount of data sources within Life Sciences has increased exponentially until pose a difficult problem to efficiently manage their integration. The data avalanche we are experiencing may be significant for a turning point in science, with a change of orientation from proprietary to publicly available data and a concomitant acceptance of studies based on the latter. LÄS MER

  7. 5. Severe reactions to foods in childhood : clinical perspectives, epidemiology and risk management

    Författare :Mirja Vetander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Food allergy is a public health issue, particularly among children, and seems to be increasing worldwide. Allergic reactions to foods vary in terms of symptoms and severity. Anaphylaxis, the most severe allergic reaction, can be fatal. Food allergy has significant negative impact in the daily lives of allergic children and their families. LÄS MER