Sökning: "hapten"
Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet hapten.
1. In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy
Sammanfattning : Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to metal ions. LÄS MER
2. Generation and evolution of human antibody repertoires
Sammanfattning : This thesis, which is based on five original papers, covers different aspects of antibody specificity and diversity, with the overall goal to understand the makeup of antibody repertoires and their functionality as they occur in vivo or as they are developed in the laboratory. Besides their importance in the adaptive immune response, antibodies have emerged as an invaluable tool in applications ranging from basic research to disease diagnostics and therapy. LÄS MER
3. Molecular mechanisms and complete antigen formation in allergic contact dermatitis
Sammanfattning : Allergic contact dermatitis (ACD) is a common T cell mediated skin disease. Small reactive organic molecules called haptens induce ACD. Haptens are not recognized by themselves, but need to bond to endogenous proteins in the skin, and processed further into complete antigens. Antigen specific T cells then recognize the resulting antigen. LÄS MER
4. Chemical studies on the true Forssman hapten, the corresponding antibody, and their interaction
Sammanfattning : .... LÄS MER
5. New insights in contact allergy and drug delivery. A study of formulation effects and hapten targets in skin using two-photon fluorescence microscopy
Sammanfattning : The skin is a remarkable barrier, protecting us from invasion of e.g. harmful microorganisms and UV-radiation. However, the skin is not adopted to resist repeated exposure to the multitude of xenobiotics introduced into modern society. LÄS MER
