Sökning: "Adenovirus early region 4"

Hittade 4 avhandlingar innehållade orden Adenovirus early region 4.

  1. 1. Function of adenovirus early region 4 proteins in RNA processing and cellular transformation

    Författare :Karin Öhman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adenovirus; Adenovirus early region 4; pre-mRNA splicing; alternative splicing; cellulartransformation.;

    Sammanfattning : For almost 30 years, adenovirus has been used as a model system for mechanistic studies of eucaryote gene expression. In this thesis, we have concentrated our efforts to investigate the function of adenovirus early region 4 (E4) gene products in cellular transformation and the post-transcriptional regulation of gene expression. LÄS MER

  3. 2. Transcriptional regulation by adenovirus early region 1 and 4 proteins

    Författare :Mattias Mannervik; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Nuclear Organization of Gene Expression in Adenovirus Infected Cells

    Författare :Anders Aspegren; Lars Wieslander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Adenovirus; mRNA; transport; IGCs; E434kDa; E1B55kDa; NES; snRNP; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Adenovirus infected cells provide a good model system for studying nuclear organization during RNA production and transport. This thesis is focused on the dynamic organization of splicing factors during the late phase of Adenovirus infection in HeLa cells, the nuclear localization of viral RNA, and the pathway used for viral RNA transport to the cytoplasm. LÄS MER

  5. 4. Transcriptional activation by Sp1 and the adenovirus E1A transactivator protein

    Författare :Anne-Christine Ström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Transcription is a key step in the regulation of gene expression. Activation of transcriptionrequires that the RNA polymerase receive both, regulatory signals from transcription factors,and initiate transcription at the correct location in the genome, at the promoter. LÄS MER