Sökning: "3T3 cells"

Visar resultat 11 - 15 av 25 avhandlingar innehållade orden 3T3 cells.

  1. 11. The role of PDGFB in dermatofibrosarcoma protuberans and giant cell fibroblastoma

    Författare :Kevin P O'Brien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dermatofibrosarcoma protuberans; giant cell fibroblastoma; translocation; FISH; translocation breakpoint; fusion gene; oncogene; Platelet derived growth factor B-chain; collagen type I alpha 1; tumor formation; autocrine stimulation;

    Sammanfattning : Dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) are rare invasive tumors of the dermis. GCF is considered the juvenile form of DFSP. Both DFSP and GCF are characterized by the presence of chromosomal aberrations involving chromosomes 17 and 22. LÄS MER

  3. 12. Decellularized liver extracellular matrix as a 3D scaffold for bioengineering applications

    Författare :Vamakshi Khati; Aman Russom; Håkan Jönsson; Giulia Gaudenzi; Ana Teixeira; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; liver decellularization; decellularized liver matrix bioink; bioprinting; sacrificial scaffold; viscoelasticity; bioengineering; tumor modeling; stem cell differentiation; bioreactor; Biotechnology; Bioteknologi;

    Sammanfattning : The increasing global burden of end-stage liver disease has increased the need for liver transplantation, the definitive cure. However, there is a huge discrepancy between the number of available organ donors and the number of patients waiting for transplantation, resulting in the deaths of a significant number of patients on the waiting list as only 10% of the global need for transplantation is met. LÄS MER

  4. 13. Factors influencing nerve growth in situ and in vitro

    Författare :Helena Jerregård; Mårten Risling; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Bakgranden till denna doktorsavhaodling är den problematik som uppstår efter en perifer nervskada, roreträdesvis i relation till handen eftersom den har så stor betydelse i vårt dagliga liv. En haod utan känsel fungerar dåligt och än sänne fungerar en handprotes. LÄS MER

  5. 14. Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis

    Författare :Hong Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The family of VEGF/PDGF growth factors and their receptors are important regulators of tumorigenesis and angiogenesis. VEGFs have been shown to play important roles in development of both blood and lymphatic vessels by effect on endothelia cells. LÄS MER

  7. 15. In vitro studies of the diabetic condition using cultured fibroblasts with focus on wound healing

    Författare :Karin M Hehenberger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :diabetes; fibroblasts; wound healing; proliferation; protein kinaseC; lactate; growth factors; resistance.;

    Sammanfattning : This thesis focuses on the diabetic condition at the cellular level, and how this may lead to late complications. Defect wound healing in diabetic patients is poorly understood, but impaired granulation is observed clinically. We have therefore decided to study an in vitro system using cultured fibroblasts. LÄS MER