Sökning: "tumor formation"

Visar resultat 1 - 5 av 331 avhandlingar innehållade orden tumor formation.

  1. 1. Utilizing Biopolymers in 3D Tumor Modeling and Tumor Diagnosis

    Författare :Negar Abbasi Aval; Torbjörn Pettersson; Aman Russom; Maria Tenje; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D tumor modeling; Spheroids; Cellulose Nano Fibrils; Layer by Layer; Extracellular matrix; Circulating Tumor Capturing; Pancreatic ductal adenocarcinoma PDAC ; 3D-tumörmodellering; Sfärer; Cellulosa; Lager-på-lager; Extracellulärmatris; Infångning av cirkulerande tumörceller; Mänskliga Duktala Adenocarcinom-Hepatocyter; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Cancer represents a significant global public health challenge and ranks as the second mostcommon cause of death in the United States. The onset of cancer entails an initial phasewhere cells lose their polarity and disconnect from the normal basement membrane, allowingthem to form distinct three-dimensional (3D) configurations that interact with adjacent cellsand the surrounding microenvironment. LÄS MER

  3. 2. The MEN 1 Pancreas : Tumor Development and Haploinsufficiency

    Författare :Margareta Halin Lejonklou; Britt Skogseid; Peter Stålberg; Andreea Barbu; Gerard Doherty; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEN 1; PNET; tumor development; haploinsufficiency; survivin; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : Multiple Endocrine Neoplasia Type I Syndrome (MEN 1) is a monogenic autosomal dominantly inherited cancer syndrome caused by a heterozygous loss of the MEN1 gene, predisposing for endocrine cell proliferation and tumor formation. MEN 1 carriers classically develop tumors in endocrine organs; the parathyroids, the endocrine pancreas, and the pituitary. LÄS MER

  4. 3. Quantitative analysis of tumor growth and response to therapy

    Författare :Esmaeil Mehrara; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; tumor; growth; response; therapy; modeling; clinical;

    Sammanfattning : Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimization of treatment strategies. However, modeling tumor growth based on clinical data is hampered by the limited data available, since therapy is in general initiated as early as possible after diagnosis. LÄS MER

  5. 4. Platelets – Multifaceted players in tumor progression and vascular function

    Författare :Yanyu Zhang; Anna-Karin Olsson; Gertraud Orend; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER

  7. 5. Tumor angiogenesis. Regulation of mural cell recruitment and endothelial sprouting

    Författare :Alexandra Abramsson; Göteborgs universitet; []
    Nyckelord :Angiogenesis; tumor; retina; PDGF; VEGF; platelet-derived growth factor; guidance; vascular endothelial growth factor.;

    Sammanfattning : The formation of new blood vessels is an inherent part of many physiological and pathological processes. Currently, there is a strong hope pathological situations like stroke, diabetic retinopathy and cancer may be affected by pharmacological regulators of blood vessel formation. LÄS MER