Sökning: "â-cell"
Visar resultat 21 - 25 av 558 avhandlingar innehållade ordet â-cell.
21. Gene expression and its physiological control in disease and development : Studies on the human PDGF-B gene and tumour hypoxia
Sammanfattning : Strict control of gene expression is essential during development and in response to physiological stimuli. This thesis describes the functional characterisation of the gene regulatory mechanisms controlling the expression of the potent human growth factor Platelet Derived Growth Factor B gene, in a cell type specific context and in response to low oxygen tension. LÄS MER
22. Functional studies of calcein acetoxymethyl ester in human tumor cells
Sammanfattning : A fluorometric assay for functional measurement of P-glycoprotein 170 (Pgp) mediated transport in cell lines, using the acetoxymethyl ester of calcein (calcein/AM) as a probe was established. The myeloma cell line RPMI 8226/S and the two Pgp-expressing doxorubicin resistant subcell lines 8226/dox6 (low) and 8226/dox40 (high) were used. LÄS MER
23. Toward a tissue engineered blood vessel. Cell cultivation, hemodynamic influences and matrix production
Sammanfattning : Cardiovascular diseases are the leading causes of mortality in the western world. Thereplacement or repair of diseased blood vessels with human autografts (vein or arteries) orsynthetic vascular grafts (ePTFE or Dacron) has become a routine treatment. Autologous graftsare not always available in all patients. LÄS MER
24. Peptidoglycan regulation of Drosophila immunity
Sammanfattning : Innate immunity is an ancient defense system that distinguishes between self and non self and is present in both vertebrates and invertebrates. Peptidoglycan (PGN), a cell wall component shared by both gram-negative and gram-positive bacteria, is the major recognition molecule for the detection of bacteria in Drosophila. LÄS MER
25. Cell cycle regulation and DNA damage response : a record of polo-like kinase 1 activity
Sammanfattning : Division and cell proliferation is an essence of life. A human cell has in its core a very simple yet a very complex machinery to coordinate cell cycle activities and events. LÄS MER