Sökning: "angiogenic factors"

Visar resultat 1 - 5 av 93 avhandlingar innehållade orden angiogenic factors.

1. 1. Angiogenic growth factors : mechanism of action and function in vascular development

   Författare :Charlotte Rolny; Andrius Kazlauskas; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; PDGF-BB; VEGF; angiogenesis; hypoxia; migration; heparin; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molecular Medicine; molekylär medicin genetik och patologi ;

   Sammanfattning : The mature vascular system is composed of a network of blood vessels organized into arteries, capillaries, and veins. The vessels are composed of endothelial cells surrounded by smooth muscle cells and embedded in a specialized basement membrane. LÄS MER

3. 2. Prognostic Factors in Malignant Melanoma

   Författare :Åsa Bolander; Michael Bergqvist; Simon Ekman; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Torgny Rasmuson; Uppsala universitet; []
   Nyckelord :Malignant melanoma; prognostic factors; survival; chemotherapy; radiation;

   Sammanfattning : Because of the failure so far to find effective treatment for patients with advanced stages of melanoma, increasing efforts have been made to find prognostic factors identifying patients in the risk zone for development of metastasis.This thesis investigates the prognostic powers of a few selected serological and immunohistochemical biomarkers. LÄS MER

4. 3. Exercise and angiogenic growth factors in human skeletal muscle

   Författare :Thomas Gustafsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adapatation; angiogenesis; angiogenic growth factors; blood flow; gene expression; gene regulation; human; ischaemia; skeletal muscle; training;

   Sammanfattning : Long-term electrical stimulation and endurance exercise increase the amount of capillaries in skeletal muscle. VEGF-A is a well-characterized stimulatory angiogenic growth factor and has shown to play an important role in angiogenesis in pathological conditions in humans and in physiological conditions in animal models. LÄS MER

5. 4. Functional characterization of pro-angiogenic neutrophils

   Författare :Jalal Lomei; Mia Phillipson; Gustaf Christoffersson; Johan Kreuger; Lars Olaf Cardell; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; leukocytes; neutrophils; pro-angiogenic neutrophils; islets transplantation; intravital microscopy; aortic ring assay; phagocytosis; ROS production; hypoxia; vascular permeability; neutrophil recruitment; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste products from cell metabolism. Angiogenesis, formation of new blood vessels by sprouting from pre-existing vessels, is one of the main mechanisms involved in blood vessel formation. LÄS MER

7. 5. Predictive Factors in Esophageal Carcinoma

   Författare :Martin Dreilich; Michael Bergqvist; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Claes Mercke; Uppsala universitet; []
   Nyckelord :Oncology; Esophageal carcinoma; Survival; Prognosis; Angiogenesis; HER-2; Telomerase; FMCA; HPV; Onkologi;

   Sammanfattning : Esophageal carcinoma is a malignancy with a poor prognosis and is the sixth cause of cancer related death worldwide. In Sweden approximately 400 new cases are diagnosed every year. The aim of this present thesis was to investigate predictive factors for esophageal carcinoma patients. LÄS MER