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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Role of tubular scattered cells of the kidney in disease and regeneration

    Författare :Krzysztof Krawczyk; Malmö Klinisk patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney Diseases; acute kidney disease; acute kidney injury; chronic kidney disease; SOX9; pIgR; Polymeric immunoglobulin receptor; Immune cells; papillary carcinoma; pRCC; Kidney cancer;

    Sammanfattning : With well over 700 000 deaths every year worldwide, kidney disease constitutes an immense health problem for patients and society. The total global number of people with kidney disease regardless of severity amounts to a staggering 600 000 000. LÄS MER

  3. 2. TGF-B signaling in Neuroblastoma and Renal Cell Carcinoma

    Författare :Anna-Karin Boström; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Renal Cell Carcinoma; ATN; Regeneration; Notch; TGF-B; EMT; Neuroblastoma; MYCN; miR-17-92;

    Sammanfattning : The tubular cells of the adult kidney are normally mitotically quiescent, in stark contrast to the massive regenerative capacity of the injured renal epithelium. In Paper I we characterized a new cell population of progenitor cells using ALDH as a selection marker. LÄS MER

  4. 3. Cytogenetic studies of normal kidney tissue and renal cell carcinoma

    Författare :Peter Elfving; Malmö (Abrahamsson) Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; Klinisk genetik; Clinical genetics; nonneoplastic kidney tissue; renal cell carcinoma; trisomy 7; Cytogenetics; FISH; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. LÄS MER

  5. 4. Hormone-related factors and breast cancer : studies of risk and prognosis

    Författare :Lena Rosenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epidemiology; breast neoplasms; body mass index; hormone replacement therapy; reproductive history; ductal carcinoma; lobular carcinoma; tubular carcinoma; estrogen receptor; progesterone receptor; risk assessment; survival;

    Sammanfattning : The main purpose of this thesis was to explore the influences of risk factors for breast cancer on breast cancer characteristics and survival. We evaluated the associations between number and timing of births and breast cancer-specific survival using data from the Swedish Cancer Register, the Swedish Cause of Death Register, and the Multi-Generation Register. LÄS MER

  7. 5. Insights into breast cancer: New familial patterns and identification of a potential predictive marker

    Författare :Carolina Ellberg; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BRCA1; BRCA2; Spider telangiectasias; Heredity; Parental inheritance; Recessive; familial; Breast cancer;

    Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER