Sökning: "Kidney Diseases"

Visar resultat 1 - 5 av 139 avhandlingar innehållade orden Kidney Diseases.

  1. 1. Role of tubular scattered cells of the kidney in disease and regeneration

    Författare :Krzysztof Krawczyk; Malmö Klinisk patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney Diseases; acute kidney disease; acute kidney injury; chronic kidney disease; SOX9; pIgR; Polymeric immunoglobulin receptor; Immune cells; papillary carcinoma; pRCC; Kidney cancer;

    Sammanfattning : With well over 700 000 deaths every year worldwide, kidney disease constitutes an immense health problem for patients and society. The total global number of people with kidney disease regardless of severity amounts to a staggering 600 000 000. LÄS MER

  3. 2. Kidney diseases : insights from omics approaches

    Författare :Jing Guo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney diseases (CKDs) affects about 11-15% of adults worldwide. When it progresses to the end-stage renal disease (ESRD), there is no effective medication for cure, the only treatment being chronic dialysis or kidney transplantation. LÄS MER

  4. 3. Podocyte Melanocortin 1 Receptor Mediated Signaling : A potential new target for patients with kidney diseases

    Författare :Johannes Elvin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Podocyte; Melanocortin 1 Receptor; actin cytoskeleton; nephrotic syndrome; adrenocorticotropic hormone; oxidative stress; RhoA; Kidney disease;

    Sammanfattning : Treatment of patients with nephrotic syndrome (NS) is currently unspecific and directed at ameliorating the symptoms rather than eliminating the cause. NS is actually a multitude of glomerular diseases characterized by poorly understood disease mechanisms and symptoms that include proteinuria, hypoalbuminemia and edema. LÄS MER

  5. 4. Molecular mechanisms of the kidney in health and disease

    Författare :Kerstin Ebefors; Göteborgs universitet; []
    Nyckelord :kidney; gene expression; glomerulus; proteoglycans;

    Sammanfattning : In 2010, 307 Swedish patients received a new kidney through transplantation, and the first of April 2011, 603 patients were on the kidney transplant waiting list. In Sweden over 8000 patients are presently in active uremic care with about half in dialysis and the other half with a functional kidney graft. LÄS MER

  7. 5. Studies on the Role of Apoptosis in Kidney Diseases

    Författare :Linnéa Nilsson; Hjalmar Brismar; Anita Aperia; Lena Scott; Fredrik Palm; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biological Physics; Biologisk fysik;

    Sammanfattning : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. LÄS MER