Sökning: "familial"

Visar resultat 1 - 5 av 423 avhandlingar innehållade ordet familial.

1. 1. Colonoscopic surveillance in familial colorectal cancer

   Författare :Anna Forsberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :familial;

   Sammanfattning : Colorectal cancer (CRC) is a disease with a high and rising incidence in the industrialized countries. It is the third leading cause of death among cancers in Sweden and the forth worldwide. Important etiological factors are both environmental and lifestyle as well as heritable factors. LÄS MER

3. 2. Familial thoracic aortic aneurysms and dissections : studies on genotype and phenotype

   Författare :Matias Hannuksela; Bo Carlberg; Bengt Johansson; Eva-Lena Stattin; Anders Gottsäter; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thoracic aorta; familial aortic aneurysm; familial aortic dissection; genetics; aortic stiffness;

   Sammanfattning : Background: Thoracic aortic aneurysms and dissections (TAAD) have a genetic component with an estimated 20-25% of the patients having a positive family history. An aneurysm often precedes a dissection. Acute aortic dissections are associated with high mortality and morbidity, even when operated on. LÄS MER

4. 3. Familial amyloidosis with polyneuropathy : studies of genetic factors modifying the phenotype of the disease

   Författare :Malin Olsson; Ole B Suhr; Lisbeth Tranebjærg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Familial amyloid polyneuropathy; Amyloidosis; Transthyretin; Allele Frequency; Mitochondria; parent-of-origin; MicroRNA; Single Nucleotide Polymorphism; 3 Untranslated Regions genetics; Medical genetics; Medicinsk genetik; Clinical genetics; Klinisk genetik; genetik; Genetics; klinisk genetik; Clinical Genetics; medicin; Medicine;

   Sammanfattning : Background. Familial Amyloidosis with Polyneuropathy (FAP) is an autosomal dominantly inherited systemic amyloid disease. The disease is caused by mutations in the transthyretin (TTR) gene, where close to 100 different amyloidogenic mutations have been identified. LÄS MER

5. 4. Insights into breast cancer: New familial patterns and identification of a potential predictive marker

   Författare :Carolina Ellberg; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BRCA1; BRCA2; Spider telangiectasias; Heredity; Parental inheritance; Recessive; familial; Breast cancer;

   Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER

7. 5. Familial occurrence of abdominal aortic aneurysms

   Författare :Örjan Norrgård; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysms; familial occurrence; serum lipids and lipoproteins; genetic markers; morphology; collagen types; vimentin; desmin;

   Sammanfattning : The occurrence of clinically diagnosed and/or ruptured abdominal aortic aneurysms (AAAs) in the families of 220 patients with AAAs, treated at the Surgical Clinic, University Hospital of Umeå in the northern part of Sweden during the years 1965-82, was studied. A questionnaire concerning the blood relatives was answered by 87/89 patients. LÄS MER