Sökning: "trypanosomiasis"

Visar resultat 6 - 10 av 16 avhandlingar innehållade ordet trypanosomiasis.

1. 6. Parasite signalling and host responses in experimental and human African trypanosomiasis

   Författare :Maha Hamadien; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :TLTF; anti-TLTF antibodies; IFN-gamma; Human African trypanosomiasis; T b. brucei; ;

   Sammanfattning : African trypanosomiasis or sleeping sickness is a disease of tropical Africa caused by the unicellular-flagellated protozoan parasite, Trypanosoma brucei (T b.), which is transmitted by its insect vector, the tsetse fly. In humans, there are two forms of the disease: a chronic form in West and Central Africa, caused by T. b. LÄS MER

3. 7. Drug Analysis : Bioanalytical Method Development and Validation

   Författare :Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
   Nyckelord :Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

   Sammanfattning : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. LÄS MER

4. 8. Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs

   Författare :Susanne Römsing; Yngve Bergqvist; Åsa Emmer; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography; Chemistry; Kemi; Analytical Chemistry; Analytisk kemi;

   Sammanfattning : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. LÄS MER

5. 9. Immunological studies in the brain and signaling pathways in experimental African trypanosomiasis

   Författare :Ahmed Sharafeldin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Trypanosoma brucei; Cytokines; Chemokines; IFN-gamma; Transcription factors;

   Sammanfattning : African Trypanosomiasis is a disease prevalent among humans and animals in tropical Africa which is caused by the extracellular hemoflagellate Trypanosoma brucei (T. b.). LÄS MER

7. 10. A role of sympathetic nervous system in immunomodulation of early experimental African trypanosomiasis

   Författare :Yajuan Liu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : African trypanosomiasis or sleeping sickness is a protozoan disease prevalent in Sub-saharan Africa. It is caused by the genus Trypanosoma and occurs in humans and animals and is transmitted by infected tsetse flies. Trypanosoma brucei (T b.) rhodesiense and T b. LÄS MER