Sökning: "transmembrane helices"

Visar resultat 21 - 25 av 32 avhandlingar innehållade orden transmembrane helices.

  1. 21. Stress, Homeostasis and Robustness: Molecular and Systems Level Analysis in Yeast

    Författare :Doryaneh Ahmadpour; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Abstract Cells constantly encounter stress due to alterations in the external milieu or internal parameters. However, cells are robust to such changes and maintain homeostasis. Using the yeast Saccharomyces cerevisiae as a model organism, we attempted to elucidate aspects of homeostasis and robustness at both molecular and systems levels. LÄS MER

  3. 22. Structure/function relationships of inorganic phosphate transporters

    Författare :Dieter R. Samyn; Bengt Persson; Hanna Sychrová; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic phosphate; transporters; Saccharomyces cerevisiae; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Sammanfattning : Of the many nutrients that make the metabolic clock tick, inorganic phosphate fulfills an essential role in all yeast (and other organisms), being necessary for both structural and metabolic purposes. In order to transport phosphate into the cell interior, Saccharomyces cerevisiae makes use of two systems, comprising high- or low-affinity transporters, which are responsible for the cellular accumulation of inorganic phosphate. LÄS MER

  4. 23. Classification, Evolution, Pharmacology and Structure of G protein-coupled Receptors

    Författare :Malin C Lagerström; Helgi B. Schiöth; Robert Fredriksson; Anthony J. Harmar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Classification; Structure; Pharmacology; Evolution; G protein-coupled receptor; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : G protein-coupled receptors (GPCR) are integral membrane proteins with seven α-helices that translate a remarkable diversity of signals into cellular responses. The superfamily of GPCRs is among the largest and most diverse protein families in vertebrates. LÄS MER

  5. 24. Voltage sensor movements in shaker and HCN channels

    Författare :Roope Männikkö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Voltage-gated ion channels are crucial for electrical signaling in living organisms. They are composed of four similar subunits with six transmembrane α-helices, S1-S6. Each subunit contains a voltage-sensing domain, S1-S4, and an ion-conducting pore domain, S5-S6. LÄS MER

  7. 25. Exploring the Interplay of Lipids and Membrane Proteins

    Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

    Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER