Sökning: "thermostability"

Visar resultat 6 - 10 av 28 avhandlingar innehållade ordet thermostability.

  1. 6. Structural studies of lumazine synthases : thermostability, catalytic mechanism and molecular assembly

    Författare :Xiaofeng Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :X-ray crystallography; lumazine synthase; thermostability; catalytic mechanism; molecular assembly;

    Sammanfattning : Riboflavin, also known as vitamin B2, is biosynthesized in plants, bacteria, archaea and fungi. The primary biological function of riboflavin is related to its existence as a component of the two coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which play an important role for electron transfer in energy metabolism. LÄS MER

  3. 7. Structural insights into the catalytic mechanism, protein dynamics, inhibition and thermostability of GH7 cellobiohydrolases

    Författare :Majid Haddad Momeni; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Glycoside hydrolase family 7 cellobiohydrolases (GH7 CBH) are typically the most abundant enzymes of cellulolytic fungi and play a key role in biomass recycling in Nature, as well as in biofuel production from plant biomass. This thesis examines molecular properties of this biologically and industrially important class of enzymes. LÄS MER

  4. 8. Structure determination, thermal stability and catalytic mechanism of hyperthermostable isocitrate dehydrogenases

    Författare :Mikael Karlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :X-ray crystallography; isocitrate dehydrogenase; thermostability; catalytic mechanism;

    Sammanfattning : In this thesis, studies on the enzyme isocitrate dehydrogenase (IDH) from the hyperthermophiles Aeropyrum pernix (ApIDH), Thermotoga maritima (TmIDH), Archaeoglobus fulgidus (AfIDH) and Pyrococcus furiosus (PfIDH) are presented. The aim of the described work was to contribute to the understanding of protein thermostability and to study the catalytic mechanism. LÄS MER

  5. 9. Structural and biochemical analysis of two copper proteins - plastocyanin from spinach and nitrite reductase from Rhodobacter sphaeroides 2.4.3

    Författare :Frida Jacobson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plastocyanin; X-ray crystallography; nitrite reductase; copper geometry; redox; copper protein; photosynthesis; reduction potential; denitrification; electron transfer;

    Sammanfattning : Plastocyanin from spinach and nitrite reductase from Rhodobacter sphaeroides 2.4.3 are two copper-containing proteins that are involved in biological electron transport chains: plastocyanin operates in photosynthesis and nitrite reductase takes part in the denitrification pathway. LÄS MER

  7. 10. An evolutionary basis for protein design and structure prediction

    Författare :Christoffer Norn; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Biophysics; Protein design; Protein structure prediction;

    Sammanfattning : The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design new protein functions. LÄS MER