Sökning: "copper protein"

Visar resultat 1 - 5 av 72 avhandlingar innehållade orden copper protein.

  1. 1. Human copper ion transfer : from metal chaperone to target transporter domain

    Författare :Moritz Sebastian Niemiec; Pernilla Wittung-Stafshede; Nigel Robinson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; copper homeostasis; copper chaperone; Atox1; ATP7B; Wilson disease protein; metal transport; size exclusion chromatography; thermodynamics; isothermal calorimetry;

    Sammanfattning : Many processes in living systems occur through transient interactions among proteins. Those interactions are often weak and are driven by small changes in free energy. LÄS MER

  3. 2. Structure and Dynamics of the Copper-binding Octapeptide Region in the Human Prion Protein

    Författare :Eva-Stina Riihimäki; Lars Kloo; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; prion protein; copper; molecular dynamics simulation; solvation model; metal ions; coordination; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : The copper-binding ability of the prion protein may be closely connected to its function. Identifying the exact function of the prion protein can clarify the underlying mechanism in prion diseases. In this work, the copper-binding octapeptide region in the human prion protein has been studied. LÄS MER

  4. 3. Studies on spinach plastocyanin and mutants : Expression in Escherichia coli, folding and function

    Författare :Mikael Ejdebäck; Örjan Hansson; Miguel A. De la Rosa; Göteborgs Universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; plastocyanin; electron transfer; copper; protein-protein interactions; protein expression; folding; site-directed mutagenesis; NMR; Naturvetenskap; Natural sciences;

    Sammanfattning : Photosynthesis is a process in which photons from sunlight excite chlorophylls in the thylakoid membranes of plants, algae and cyanobacteria. The photo-oxidised reaction centre chlorophyll P700 is re-reduced by an electron transferred from the soluble, blue copper protein plastocyanin. LÄS MER

  5. 4. Protein folding studies of human superoxide dismutase and ALS associated mutants

    Författare :Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Sammanfattning : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. LÄS MER

  7. 5. Structural and biochemical analysis of two copper proteins - plastocyanin from spinach and nitrite reductase from Rhodobacter sphaeroides 2.4.3

    Författare :Frida Jacobson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plastocyanin; X-ray crystallography; nitrite reductase; copper geometry; redox; copper protein; photosynthesis; reduction potential; denitrification; electron transfer;

    Sammanfattning : Plastocyanin from spinach and nitrite reductase from Rhodobacter sphaeroides 2.4.3 are two copper-containing proteins that are involved in biological electron transport chains: plastocyanin operates in photosynthesis and nitrite reductase takes part in the denitrification pathway. LÄS MER