Sökning: "tailored treatment"

Visar resultat 26 - 30 av 166 avhandlingar innehållade orden tailored treatment.

  1. 26. On the Diagnosis and Treatment of Lumbar Spinal Stenosis

    Författare :Konstantinos Pazarlis; Peter Försth; Bengt Sandén; Nikos Schizas; Karl Michaëlsson; Christian Hellum; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lumbar spinal stenosis; spine surgery; decompression; fusion; sagittal balance; electrodiagnosis; neurophysiology; Orthopaedics; Ortopedi; Neurology; Neurologi; Radiology; Radiologi;

    Sammanfattning : Lumbar spinal stenosis (LSS) is the most common indication for spinal surgery. The aging global population is increasing the demand for strategies that promote physical activity among the elderly. As the prevalence of LSS rises, the condition gains constantly demographic and socioeconomic attention. LÄS MER

  3. 27. New Paradigms in GPCR Drug Discovery : Structure Prediction and Design of Ligands with Tailored Properties

    Författare :Mariama Jaiteh; Jens Carlsson; David E Gloriam; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G Protein-Coupled Receptor; Molecular Docking; Virtual Screening; Homology Modeling; Molecular Dynamics Simulation; Chemical Library; Functionally Selective Ligand; Polypharmacology; Dimerization; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : G protein-coupled receptors (GPCRs) constitute a large superfamily of membrane proteins with key roles in cellular signaling. Upon activation by a ligand, GPCRs transduce signals from the extracellular to the intracellular environment. LÄS MER

  4. 28. Mitigating Off-Gassing and Self-Heating in Fuel Wood Pellets Storage : A Raw Materials Selection and Pre-Treatment Centred Approach

    Författare :Workson Siwale; Jonas Berghel; Gunnar Henriksson; Michael Finell; Stefan Frodeson; Mani Sudhagar; Karlstads universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; solid biofuels; densified biomass; heat generation; off-gas emissions; carbon monoxide; carbon dioxide; methane; fatty and resin acids; Miljö- och energisystem; Environmental and Energy Systems;

    Sammanfattning : Wood pellets have become a preferred solid biomass fuel for heat and power generation due to their standardized nature, known properties, and consistent quality. However, pellets produced from fresh sawdust sometimes undergo self-heating and off-gassing during storage. This poses a challenge for their transportation and storage. LÄS MER

  5. 29. Aspects of Endocrine Therapy in Primary Breast Cancer. Risk Profiling and Adherence Perspectives for Improving Tailored Adjuvant Treatment

    Författare :Christine Lundgren; LUCC: Lunds universitets cancercentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Abstract: Breast cancers are heterogeneous tumours. Prognostic markers are needed to better profile the patient´s risk, and predictive markers to indicate the expected benefit of systemic treatment. Using gene expression analyses, breast tumours can be divided into intrinsic subtypes. LÄS MER

  7. 30. Development of DNA origami-based tools for cancer treatment

    Författare :Yang Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : DNA has been used as material for the assembly of objects at different scales. Particularly, the introduction of DNA origami has been inspiring the design and construction of many different versions of DNA nanostructures for, especially, biomedical applications. LÄS MER