Sökning: "Polypharmacology"

Hittade 1 avhandling innehållade ordet Polypharmacology.

  1. 1. New Paradigms in GPCR Drug Discovery : Structure Prediction and Design of Ligands with Tailored Properties

    Författare :Mariama Jaiteh; Jens Carlsson; David E Gloriam; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; G Protein-Coupled Receptor; Molecular Docking; Virtual Screening; Homology Modeling; Molecular Dynamics Simulation; Chemical Library; Functionally Selective Ligand; Polypharmacology; Dimerization; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : G protein-coupled receptors (GPCRs) constitute a large superfamily of membrane proteins with key roles in cellular signaling. Upon activation by a ligand, GPCRs transduce signals from the extracellular to the intracellular environment. LÄS MER