Sökning: "solid-state nanopore"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden solid-state nanopore.

  1. 1. Solid-state nanopores : fabrication and applications

    Författare :Shuangshuang Zeng; Zhen Zhang; Amit Meller; Uppsala universitet; []
    Nyckelord :solid-state nanopore; truncated-pyramidal nanopore; nanopore array; pore size reduction; individual addressability; microfluidics; translocation.; Teknisk fysik med inriktning mot elektronik; Engineering Science with specialization in Electronics;

    Sammanfattning : Nanopores are of great interest in study of DNA sequencing, protein profiling and power generation. Among them, solid-state nanopores show obvious advantages over their biological counterparts in terms of high chemical stability and reusability as well as compatibility with the existing CMOS fabrication techniques. LÄS MER

  3. 2. Solid-State Nanopores for Sensing : From Theory to Applications

    Författare :Chenyu Wen; Shi-Li Zhang; Zhen Zhang; Ulrich F. Keyser; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; solid-state nanopore; ionic current; current blockage; effective transport length; noise; surface charge; translocation; biomolecule; electroosmotic flow; vortex; autogenic translocation; multiple nanopores; Teknisk fysik med inriktning mot elektronik; Engineering Science with specialization in Electronics;

    Sammanfattning : Nanopore based sensing technology has been widely studied for a broad range of applications including DNA sequencing, protein profiling, metabolite molecules, and ions detection. The nanopore technology offers an unprecedented technological solution to meeting the demands of precision medicine on rapid, in-field, and low-cost biomolecule analysis. LÄS MER

  4. 3. Engineering Surfaces of Solid-State Nanopores for Biomolecule Sensing

    Författare :Shiyu Li; Shi-Li Zhang; Michael Mayer; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; solid-state nanopores; surface engineering; DNA sensing; DNA polymerase; optical detection; lipid bilayer; hafnium oxide; electron beam induced deposition;

    Sammanfattning : Nanopores have emerged as a special class of single-molecule analytical tool that offers immense potential for sensing and characterizing biomolecules such as nucleic acids and proteins. As an alternative to biological nanopores, solid-state nanopores present remarkable versatility due to their wide-range tunability in pore geometry and dimension as well as their excellent mechanical robustness and stability. LÄS MER

  5. 4. Silicon Nanopore Arrays : Fabrication and Applications for DNA Sensing

    Författare :Miao Zhang; Jan Linnros; Meni Wanunu; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanopore; array; electrochemical etching; DNA; optics; thermophoresis;

    Sammanfattning : Nanopore biomolecule sensing and sequencing has emerged as a simple but powerful tool for single molecule studies over the past two decades. By elec- trophoretically driving single molecules through a nanometer-sized pore, often sitting in an insulating membrane that separates two buffer solutions, ionic current blockades can be detected to reveal rich information of the molecules, such as DNA length, protein size and conformation, even nucleic acid se- quence. LÄS MER

  7. 5. Computational studies of DNA sequencing with graphene nanopores

    Författare :Lijun Liang; Yaoquan Tu; Alexander Lyubartsev; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA sequencing; Graphene nanopore; Molecular dynamic simulation; Kemi; Chemistry;

    Sammanfattning :     The aim of DNA sequencing is to obtain the order of DNA composition comprising the base pairs A (adenine) T (thymine), and C (cytosine) G (guanine). The fast development of DNA sequencing technology allows us to better understand the relationships among diseases, inheritance, and individuality. LÄS MER