Sökning: "nanopore"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet nanopore.

  1. 1. Silicon Nanopore Arrays : Fabrication and Applications for DNA Sensing

    Författare :Miao Zhang; Jan Linnros; Meni Wanunu; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; nanopore; array; electrochemical etching; DNA; optics; thermophoresis;

    Sammanfattning : Nanopore biomolecule sensing and sequencing has emerged as a simple but powerful tool for single molecule studies over the past two decades. By elec- trophoretically driving single molecules through a nanometer-sized pore, often sitting in an insulating membrane that separates two buffer solutions, ionic current blockades can be detected to reveal rich information of the molecules, such as DNA length, protein size and conformation, even nucleic acid se- quence. LÄS MER

  2. 2. Solid-state nanopores : fabrication and applications

    Författare :Shuangshuang Zeng; Zhen Zhang; Amit Meller; Uppsala universitet; []
    Nyckelord :solid-state nanopore; truncated-pyramidal nanopore; nanopore array; pore size reduction; individual addressability; microfluidics; translocation.; Teknisk fysik med inriktning mot elektronik; Engineering Science with specialization in Electronics;

    Sammanfattning : Nanopores are of great interest in study of DNA sequencing, protein profiling and power generation. Among them, solid-state nanopores show obvious advantages over their biological counterparts in terms of high chemical stability and reusability as well as compatibility with the existing CMOS fabrication techniques. LÄS MER

  3. 3. From Macro to Nano : Electrokinetic Transport and Surface Control

    Författare :Gaspard Pardon; Wouter van der Wijngaart; Philippe Renaud; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; microsystem; nanosystem; microfluidic; nanofluidic; surface modification; surface property; electrokinetics; model; simulation; material; polymer; thiol-ene; microfabrication; nanofabrication; micromanufacturing; nanomanufacturing; breath sampling; aerosol precipitation; corona discharge; electrostatic precipitation; grafting chemistry; click chemistry; nanopore; nanoporous membrane; photolithography; photopatterning; photografting; microfluidics; nanofluidics; oste; OSTE ; OSTEmer; lab-on-chip; loc; point-of-care; poc; biocompatibility; diagnostics; breath analysis; fuel cell; Electrical Engineering; Elektro- och systemteknik; Materials Science and Engineering; Teknisk materialvetenskap; Physics; Fysik; Medicinsk teknologi; Medical Technology;

    Sammanfattning : Today, the growing and aging population, and the rise of new global threats on human health puts an increasing demand on the healthcare system and calls for preventive actions. To make existing medical treatments more efficient and widely accessible and to prevent the emergence of new threats such as drug-resistant bacteria, improved diagnostic technologies are needed. LÄS MER

  4. 4. Solid-State Nanopores for Sensing : From Theory to Applications

    Författare :Chenyu Wen; Shi-Li Zhang; Zhen Zhang; Ulrich F. Keyser; Uppsala universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; solid-state nanopore; ionic current; current blockage; effective transport length; noise; surface charge; translocation; biomolecule; electroosmotic flow; vortex; autogenic translocation; multiple nanopores; Teknisk fysik med inriktning mot elektronik; Engineering Science with specialization in Electronics;

    Sammanfattning : Nanopore based sensing technology has been widely studied for a broad range of applications including DNA sequencing, protein profiling, metabolite molecules, and ions detection. The nanopore technology offers an unprecedented technological solution to meeting the demands of precision medicine on rapid, in-field, and low-cost biomolecule analysis. LÄS MER

  5. 5. Computational studies of DNA sequencing with graphene nanopores

    Författare :Lijun Liang; Yaoquan Tu; Alexander Lyubartsev; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; DNA sequencing; Graphene nanopore; Molecular dynamic simulation; Kemi; Chemistry;

    Sammanfattning :     The aim of DNA sequencing is to obtain the order of DNA composition comprising the base pairs A (adenine) T (thymine), and C (cytosine) G (guanine). The fast development of DNA sequencing technology allows us to better understand the relationships among diseases, inheritance, and individuality. LÄS MER