Sökning: "scaffold"

Visar resultat 16 - 20 av 308 avhandlingar innehållade ordet scaffold.

  1. 16. Decellularized liver extracellular matrix as a 3D scaffold for bioengineering applications

    Författare :Vamakshi Khati; Aman Russom; Håkan Jönsson; Giulia Gaudenzi; Ana Teixeira; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; liver decellularization; decellularized liver matrix bioink; bioprinting; sacrificial scaffold; viscoelasticity; bioengineering; tumor modeling; stem cell differentiation; bioreactor; Biotechnology; Bioteknologi;

    Sammanfattning : The increasing global burden of end-stage liver disease has increased the need for liver transplantation, the definitive cure. However, there is a huge discrepancy between the number of available organ donors and the number of patients waiting for transplantation, resulting in the deaths of a significant number of patients on the waiting list as only 10% of the global need for transplantation is met. LÄS MER

  2. 17. Modification of polymeric particles via surface grafting for 3D scaffold design

    Författare :Robertus Wahyu Nayan Nugroho; Ann-Christine Albertsson; Orlando J. Rojas; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; surface grafting; PLA; PLLA; hydrophilic polymers; particles; geometry; steric stabilization; atomic force microscopy AFM ; polyelectrolyte multilayers; 3D scaffold; bone tissue engineering; surface degradation;

    Sammanfattning : Surface modification techniques have played important roles in various aspects of modern technology. They have been employed to improve substrates by altering surface physicochemical properties. LÄS MER

  3. 18. degradable electroactive polymers: Synthesis, Macromolecular architecture and scaffold design

    Författare :Baolin Guo; Ann-Christine Albertsson; Patric Jannasch; KTH; []
    Nyckelord :Poly lactide ; poly ε-caprolactone ; ring-opening polymerization; carboxyl-capped aniline trimer; carboxyl-capped aniline pentamer; phenyl amino-capped aniline tetramer; coupling reaction; DCC DMAP system; degradability; electroactivity; conductivity; macromolecular architecture; chitosan; hydrogel; block copolymer; functionalization; oxidative coupling reaction; self-assembly; toxicity; tubular porous scaffold; neural tissue engineering.;

    Sammanfattning : Electrically conducting polymers induce specific cellular responses at the molecular level. One of the crucial limitations of the use of conducting polymers in tissue engineering is their inability to degrade. LÄS MER

  4. 19. Design of Functional Degradable Aliphatic Polyesters and Porous Tissue Engineering Scaffolds

    Författare :Peter Plikk; Ann-Christine Albertsson; Marek Kowalczuk; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ring-opening polymerization; Stannous octoate; 2; 2’-azoisobutyronitrile; 1; 5-dioxepane-2-one; ε-caprolactone; L-lactide; Trimethylene carbonate; 2-methylene-1; 3-dioxe-5-pene; Copolymer; Porous scaffold; Porous tubular scaffold; Electron beam; Gamma irradiation; Polymer chemistry; Polymerkemi;

    Sammanfattning : The regeneration of damaged tissues or organs using porous scaffolds which act as temporary guides for the patient’s own cells, i.e. tissue engineering, is a means to overcome the shortcomings of current standard medical treatments. LÄS MER

  5. 20. Statistical molecular design, QSAR modeling, and scaffold hopping – Development of type III secretion inhibitors in Gram negative bacteria

    Författare :Markus Dahlgren; Mikael Elofsson; Bo Nordén; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Statistical molecular design; QSAR; synthesis; type III secretion; virulence; scaffold hopping; Bioorganic chemistry; Bioorganisk kemi; datorlingvistik; computational linguistics;

    Sammanfattning : Type III secretion is a virulence system utilized by several clinically important Gram-negative pathogens. Computational methods have been used to develop two classes of type III secretion inhibitors, the salicylidene acylhydrazides and the acetylated salicylanilides. LÄS MER