Sökning: "scaffold"
Visar resultat 21 - 25 av 308 avhandlingar innehållade ordet scaffold.
21. Engineering alternative scaffold proteins for conditional targeting
Sammanfattning : Engineering naturally occurring proteins enables us to customize affinity domains according to our specific needs, tailoring them to become an important tool in a wide array of applications limited merely by our creativity. One of nature’s ways to regulate protein activity is by creating a functional change through alteration of a protein’s tertiary structure upon interaction with metal ions. LÄS MER
22. Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors Incorporating a P2 Cyclopentane-Derived Scaffold
Sammanfattning : This thesis describes the design, synthesis and structure-activity relationships analysis of potential inhibitors targeting the hepatitis C virus (HCV) NS3 protease. Also discussed is the disease caused by HCV infection and the class of enzymes known as proteases. LÄS MER
23. Synthetic Pathways to Aliphatic Polyesters and Scaffold Design
Sammanfattning : As the field of tissue engineering progresses, a continuous development of scaffold fabrication techniques and suitable degradable materials is required to obtain scaffolds with tunable characteristics. This thesis has focused on the development of pathways to synthesize degradable aliphatic polyesters and on the design of highly porous scaffolds from this class of materials. LÄS MER
24. TRÖGER´S BASE AS SCAFFOLD FOR SYNTHETIC RECEPTORS
Sammanfattning : This work focuses on the use of the Tröger´s base as organic scaffold for the construction of synthetic receptors for different classes of organic molecules. The structural properties of the Tröger's base, i.e. chirality, rigidity and curvature, allow for synthetic modifications towards the recognition of different molecules. LÄS MER
25. A three dimensional scaffold for single staged tissue engineering
Sammanfattning : Study I. Aims: Evaluate a collagen-PCL scaffold with minced bladder mucosa in vitro. M&M: Minced tissue was cultured on top of the scaffold. Scaffold properties were evaluated. LÄS MER