Sökning: "repression"

Visar resultat 16 - 20 av 282 avhandlingar innehållade ordet repression.

  1. 16. Towards a comprehensive modeling framework for studying glucose repression in yeast

    Författare :Linnea Österberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; budding yeast; glucose repression; metabolism; mathematical modelling; signaling;

    Sammanfattning : The yeast Saccharomyces cerevisiae is an important model organism for human health and for industry applications as a cell factory. For both purposes, it has been an important organism for studying glucose repression. LÄS MER

  3. 17. Dynamic regulation of the Mig1 transcriptional repressor under glucose de/repression

    Författare :Sviatlana Shashkova; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell signalling; glucose repression; Mig1; phosphorylation; Saccharomyces cerevisiae;

    Sammanfattning : The budding yeast Saccharomyces cerevisiae AMP-activated protein kinase/SNF1 is a member of a highly conserved protein family present in all eukaryotes. Snf1 regulates energy homeostasis; in yeast, it is best-known for its role in cellular adaptation to glucose limitation. LÄS MER

  4. 18. Molecular mechanisms of transcriptional repression by the orphan receptor SHP

    Författare :Ann Båvner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nuclear receptor; repression; small heterodimer partner; co-regulator;

    Sammanfattning : SHP (Small Heterodimer Partner) is an atypical orphan member of the mammalian nuclear receptor family that consists of only a putative ligand-binding domain and thus cannot bind DNA. The aim of this thesis was to investigate the molecular mechanisms of the transcriptionally inhibitory effect of SHP. LÄS MER

  5. 19. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression

    Författare :Eshagh Dorafshan Esfahani; Yuri B. Schwartz; Jan Larsson; Dale Dorsett; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Trithorax Group proteins; Polycomb Group proteins; PRC1; PRC2; PRE; histone methylation; histone ubiquitylation; Ash1; SET domain; H3K36; H3K27; Drosophila;

    Sammanfattning : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. LÄS MER

  7. 20. Coercion and its Effects : Evidence from the Israel-Palestine Conflict

    Författare :Sophia Hatz; Håvard Hegre; Kristine Eck; Allan Dafoe; Yuri Zhukov; Uppsala universitet; []
    Nyckelord :Civil conflict; state repression; counterinsurgency; coercion; Israel-Palestine conflict; Peace and Conflict Research; Freds- och konfliktforskning;

    Sammanfattning : Counterinsurgency, state repression and other forms of coercion have multiple adverse effects. Although a state’s use of threats and force should deter an opposition group, these measures often stimulate resistance. LÄS MER