Sökning: "Trithorax Group proteins"

Hittade 1 avhandling innehållade orden Trithorax Group proteins.

1. 1. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression

   Författare :Eshagh Dorafshan Esfahani; Yuri B. Schwartz; Jan Larsson; Dale Dorsett; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Trithorax Group proteins; Polycomb Group proteins; PRC1; PRC2; PRE; histone methylation; histone ubiquitylation; Ash1; SET domain; H3K36; H3K27; Drosophila;

   Sammanfattning : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. LÄS MER